Secretome from #CholesterolCrystal /CC-treated👤aortic #SmoothMuscleCell , but not CC itself, activates Neutrophil adhesion, ROS & #NeutrophilExtracellularTrap #NET
A role of SMC-derived IL-33
Polarized light to image intracellular CC
Chemical screening for CC uptake machinery in…
#CD177 + cells
➡️important role in initiation of #BiliaryAtresia pathogenesis via #NeutrophilExtracellularTrap formation
#Nacetylcysteine administration:
⬇️CD177+ cell numbers
⬇️reactive oxygen species levels
✅potential beneficial effect
🔓bit.ly/3acfQG8
#LiverTwitter
Article from Scientific Reports! #NeutrophilExtracellularTrap -enriched supernatants carry #microRNAs able to modulate TNF-α production by #macrophages . | Author: Wilson Savino
doi.org/10.1038/s41598…
#Hypertensin #NeutrophilExtracellularTrap
Important evidence on Neutrophil in cell/organ damage in #EssentialHypertension
Angiotensin II --> #NETosis + potential roles of NADPHoxidase2 & #Autophagy
Dr Panagiotis Skendros lab JCI insight 2021 Panagiotis Skendros
insight.jci.org/articles/view/…
The main mechanisms that may contribute to the development of #autoimmunity in #COVID 19 are the following
1) hyper-activation of the immune system
2) the induction of excessive #neutrophilextracellulartrap formation
3) #SARSCoV2 cross-reaction with self-components of the host
Chronic stress contributes to increased rates of metastasis and poor prognosis in #patientswithcancer . Now, Mikala Egeblad and group establish that stress induces #neutrophilextracellulartrap (NET) formation to promote metastasis.
Check out our highlight 👇
go.nature.com/3VTyl7z
#pathogens
Article: Response of Human Neutrophil Granulocytes to the Hyphae of the Emerging #Fungal Pathogen #Curvularialunata
By Eszter Judit Tóth, Tamás Papp University of Szeged, et al.
👉mdpi.com/2076-0817/9/3/…
#Phaeohyphomycosis
#NeutrophilExtracellularTrap
Chronic stress contributes to increased incidence of metastasis + poor prognosis in patients with cancer.
He et al. (Mikala Egeblad) established that stress induces #neutrophilextracellulartrap (NET) formation to promote metastasis.
For more deets, check out my latest highlight 👇
#Friend or #foe ? #neutrophils protect from #infections , but #NETosis causes #gallstone formation! Immunity ImmunoSCOPE Immune Regulation News #kidney #net #neutrophilextracellulartrap #ROS cell.com/immunity/fullt…
' #GutMicrobiome #dysbiosis contributes to #AbdominalAorticAneurysm by promoting #neutrophil #extracellular trap formation', a Cell Host & Microbe article.
#microbiota #NeutrophilExtracellularTrap #butyrate
👇
doi.org/10.1016/j.chom…
Cell membrane derived liposomes loaded with DNase I target neutrophil extracellular traps which inhibits colorectal cancer liver metastases.
| Xinyi Jiang 山东大学 SHANDONG UNIVERSITY |
#liposome #cellmembrane #DNase #NeutrophilExtracellularTrap
doi.org/10.1016/j.jcon…
Antibody-modified DNase I micelles specifically recognize the neutrophil extracellular traps (NETs) and promote their degradation.
| Vladimir P. Torchilin Chemical Engineering at Northeastern University |
[50 days' free access]
#neutrophilextracellulartrap #micelle
authors.elsevier.com/a/1gNHrcI2~~Jx0
The research focused on studying the impact of ginger supplementation on a type of white blood cell called the #neutrophil . The study was especially interested in #neutrophil extracellulartrap formation, also known as #NETosis , and what it may mean for controlling inflammation.
Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19
Dr. Cécile Oury, Philippe Delvenne, Thomas Marichal groups, J Exp Med. 2020 Oury Cécile Université de Liège
#NeutrophilExtracellularTrap
rupress.org/jem/article/21…