Neutrophil margination in a blood vessel.
In inflammation, capillary permeability increases + endothelial cells express adhesion molecules that bind to and slow down circulating neutrophils, allowing them to eventually pass through vessels into tissue.
#pathology
Our new paper is out in Science Advances! We discovered a novel mechanism for how #neutrophils fight bacterial #infections in skin that we leveraged as a #therapy . Universitätsklinikum Würzburg Johns Hopkins Medicine Hopkins Dermatology #dermtwitter #NETosis #Immunology
science.org/doi/10.1126/sc…
An inflammatory role in atherogenesis? This trial showed colchicine (a neutrophil chemotactic inhibitor) to reduce cardiovascular events in patients with CAD. LoDoCo2 Trial, NEJM 2020 ♥️
#CardioTwitter
Our research on inflammation and thrombotic and infection outcomes after IVH led by Weill Cornell Neurology PGY-2 Safa Kaleem, MD, MHS and supported by Wendy Ziai Hooman Kamel Alex Merkler CenAi Zhang Johns Hopkins Neurosciences Critical Care link.springer.com/article/10.100…
🚨New #RPTHIllustratedReview on Poststroke Venous Thromboembolism & Neutrophil Activation 🚨 (Part 1)
bit.ly/3NnroqO
Nirav Dhanesha Junaid Ansari Nilesh Pandey Harpreet Kaur