Say hi to exosomes.

Exosomes are extracellular vesicles released by our cells that assist the body in healing.

There are no “viruses”

We're excited to finally share Light-induced Extracellular Vesicle Adsorption (LEVA), a versatile technique for the scalable, high-resolution, and rapid micropatterning of EVs, from migrasomes to bacterial OMVs. biorxiv.org/cgi/content/sh…

Research| Based on single-cell #transcriptomics of arterial grafts, Hu, Dai, Chang et al. identify factors that prevent extracellular matrix deposition and #fibrosis and improve the outcomes of coronary artery bypass grafting. doi.org/10.1038/s44161…
👉 rdcu.be/dF7EV

Migraine sufferers:
New paper suggests migraines are caused by 'a lack of sufficient sodium in the extracellular space of sensory neurons' leading to 'failed action potentials.' The author has been treating 'migraineurs' for decades, and I know her to be a curious and…

Baking soda - a potential therapeutic for viral disease.

Extracellular acidity:

‣ Enhances inflammation
‣ Promotes viral replication
‣ Impairs glucocorticoid clearance
‣ Impairs glucose metabolism

Small doses of baking soda can rapidly correct this acidity.

The paper titled, “Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer’s disease mice,” demonstrated that NLRP1 and pyrin inflammasomes, and caspase-1 and ASC were significantly elevated in the cortex of mouse models of Alzheimer’s disease.

Educational Review: Myocardial extracellular volume quantification with computed tomography—current status and future outlook. (Giulia Cundari et al., Alkadhi)

#InsightsIntoImaging

🔗 buff.ly/49RpvKT

Read our latest publication!
sciencedirect.com/science/articl…

We discuss the potential of plant-derived extracellular vesicles (PDEVs) as smart nano drug delivery systems for antioxidant vitamins C and E in Alzheimer's disease (AD).

The prevalence of AD is rising due to an aging…

The cell danger response (CDR) is triggered by the mitochondria sensing the environment and through increasing extracellular ATP signalling, induces the cycle.

The mitochondria sense both psychological / environmental stressors.

CDR is activated by ATP on purinergic receptors…

Had a great time hosting Dr. Gagan Deep from Wake Forest Medical School and learning about extracellular vesicles and their role in neurodegenerative disease. UF Microbiology #Proteostasis

Some components of the extracellular matrix.

#Extracellularvesicles were able to transport therapeutic #RNA molecules across the gut barrier in advanced laboratory models of the human intestine. In animal studies (mice), the RNA-loaded milk EVs reduced #IBD -related inflammation. - King's College London exosome-rna.com/cows-milk-extr…

🚨GSEV April 2024 Newsletter 🚨

My lab is recruiting!
Looking for a PhD student and a postdoc to work on fully funded projects related to mitochondrial extracellular vesicles and mitochondrial dynamics.

I think this is an amazing story of Geobacter and Clostridium merging and sharing metabolic capabilities.
academic.oup.com/ismecommun/adv…

Our very own Michael Sulu will be giving a Spring Into STEM 2.0 talk titled:
'How we can use the cellular postal service (extracellular vesicles) to help us design better treatments for diseases? How do we sustainably feed a global population?'
19 June
ucl.ac.uk/engineering/st…

Great presentation by Pierre Villeneuve AOCS (The American Oil Chemists' Society) 'Extracellular vesicles from olive co-products and their anti-oxidant properties'. Congrats Pierre! A nice collaboration Cirad IATE QualiSud Laboratoire CarMeN (Pascal Colosetti, Anne Mey) 😊
#lipid #vesicles #antioxidant #AOCS2024

📝Title: Breaking free: endocytosis and endosomal escape of extracellular vesicles

👥Authors: Laís Ribovski, Bhagyashree Joshi, Jie Gao, Inge Zuhorn

🔗oaepublish.com/articles/evcna…

Welcome to read. 🫶 University of Groningen #EVs #exosome

Extracellular vesicles: new bullets in the fungal armory dlvr.it/T61KGq

We kick off the final session of the day with Dr David Willnow from the J.P. Vincent Lab @jpvincentlab.bsky.social The Crick presenting his research on extracellular Wnt transport mechanisms.

#WntUK2024