A quick cartoon on hairy cell leukemia to help you revise the salient points.
Hairy cell- the projections from cytoplasmic resembling hair
Leukemia- tumor cells are in blood means they have originated from bone marrow.
#pathodoodles #pathology #pathology residents #hemepath

Hairy cell leukemia involving blood/marrow. Patient presented with cytopenias. Marrow not terribly hypercellular, so very easy to overlook an infiltrate like this if the flow isn't positive. #hemepath #pathology

2 year old male with multiple lymphadenopathy 🔬
⁃Marked sinus expansion
⁃Large histiocytes
⁃Emperipolesis

IHC:
S100(+)
CD207(-)
CD1a (-)

DX: Rosai-Dorffman disease

#Hemepath #PediPath #SurgPath #pathology #PathBoards

Toño Navarro, M.D.
Luis Humberto Cruz C

(H&E, 600x) Lung, interalveolar septum #histology #anatomy #pathology #oncology #cancer #lung #emphysema #medschool #mayoclinic #usmle

😥A young patient with an alveolar sarcoma (AS) in the oral cavity operated in her adolescence and 10y after numerous metastatic foci (lung - pics, brain and breast).
Metastasis from AS: 1st manifestation or very late in the course of the disease.

#bstpath #pathology

Striking mucinous pattern with giant cells in this metastatic lung adenocarcinoma. #pathology #neuropath #pathtwitter

👩🏻‍⚕️Day 111: I’ll call this piece “the field of aspergillus” 👩🏻‍🎨 it’s kind of like a field of flowers 💐 but much less likely to smell nice and waaaaaay more likely to cause lung infections in immunocompromised patients. #pathart #pathology #microbiology

Normal bowel has +calretinin intrinsic nerve fibers without cholinergic extrinsic nerve 'hypertrophy'
Hirschsprung bowel shows loss of calretinin and ropey staining for AChE/ChT
🖼️🙏Dr. Raj P. Kapur
pathologyoutlines.com/topic/colonhir…
#GIPath #PathTwitter #PediPath
✅B for #1, #2, & #3

2/2
Immunostain shown is CD99
CK and EMA neg
FISH: EWSR1 rearrangement

🔬 Superficial Ewing sarcoma

Here is a review on superficial ES:
ncbi.nlm.nih.gov/m/pubmed/23327…

And another one on cutaneous/superficial neoplasms with EWSR1 rearrangement:
ncbi.nlm.nih.gov/m/pubmed/23399…

#BSTPath

@histiocytosisX Seriously...

Med school ----------------> Now
🤔 😭
EWSR EWSR
= =
Ewing Barely better
sarcoma than H&Es

This angiomatoid (malignant) fibrous histiocytoma has a lymphoid cuff at low magnification and hemorrhagic cystic spaces. This example shows desmin expression. These pediatric tumors usually behave indolently with rare aggressive behavior. innovativepathologypress.com

Colloid scalloping in a thyroid with Graves disease ~ #endocrine #pathology #thyroid #PathArt

17 WGA termination for cyclops, holoprosencephaly, omphalocele for Trisomy 13.
What do we have in the #Placenta ?

#PediPath #Placenta Pathology #Perinatal

Florid invaginations of sinonasal epithelium? Don't forget to look at the stroma! Case 1 is respiratory epithelial adenomatoid hamartoma- admixed benign epithelium and stroma. Case 2 is biphenotypic sinonasal sarcoma- malignant stroma entraps benign reactive epithelium. #ENTPath

Omentum. Male 23yo #GIPath #Granuloma

Benign and impressively photogenic - Cells from a Lung lavage. (Cytospin)

Let’s “Molding” “molding” and hugging 😂 … pleural fluid showing those Small cell undifferentiated Carcinoma. #PathTwitter

Some have thicker vascular walls but still with hyperostosis

Calvarial hemangioma #PediPath #BSTpath

━ 𝑴𝑰𝑵𝑯 𝑯𝑼𝒀𝑵𝑯, 𝑴.𝑫. 🌈 Leduc, Valerie tahminasultana

This one really imitates ☀️ of the X-Ray

#BSTpath #PediPath