Can you make the diagnosis from one high-power image or is it #TooCloseToDiagnose ?
Which IHC would you do to support the dx?

#PathTwitter #BSTPath #Hemepath

#hemepath examples of Dutcher bodies in plasma cell myeloma. They are composed of immunoglobulin that sits on top of nucleus (they are not true nuclear inclusions)

#hemepath acute monocytic leukemia with hemophagocytosis by blasts

#hemepath

Please also check out the recently released Chronic myelomonocytic #leukemia : 2024 update on Dx, risk stratification and management from Drs. Mrinal Patnaik & Ayalew Tefferi
Including #CMML clonal evolution & unique associations
Free access: doi.org/10.1002/ajh.27…
#hemepath

#hemepath a handful of 'flame cells' from myeloma. These are most often IgA positive.

32 years old male with recurrent pelvic calculi, history of left nephrectomy planned for renal transplant. Referred from urology for unexplained cytopenias. How does bone marrow biopsy add to his story?

#hemepath #hematology #pathtwitter #pathx

My first as a sign out :)

Just a reminder that CD10 negative FL exists (BCL2::IgH rearranged, flow CD10 very negative). We don’t have other GC markers. It was called MZL for a long time, but morphology and genetics is very FL. #PathTwitter #hemepath

#hemepath Bone marrow in patient with cystinosis

#hemepath Nice case of hairy cell. IHC BRAF (weak) and CD103

The most picturesque/textbook example of AITL you will see in 2024…
What the WHO 5th now refers to as “Nodal T follicular helper cell lymphoma, angioimmunoblastic type”

why is that.. you may ask??🧐
Allow me to tell you why…🧵1/
#hemepath

Horning the career and contributions of Dr. Medeiros to #hemepath tonight
We are proud to be his students!!!

#hemepath marginal zone lymphoma with cytoplasmic granules

Plasma cell leukemia with aggressive and aberrant plasma cells. #hemepath #PathTwitter #multiplemyeloma

Guaranteed to be the best thing you'll hear today. ⁦Weill Cornell Medicine Pathology⁩ ⁦General Internal Medicine⁩ #hemepath #hematopathology pca.st/episode/f6ad49…

#hemepath an Auer rod like structure seen in myeloma.

#hemepath CD34 IHC highlighting intravascular hematopoiesis in an MPN

#HEMEPATH Update on Cutaneous T-Cell Lymphomas and Lymphoproliferative Disorders
(Dr. David S. Cassarino, MD, Consultant Dermatopathologist, Southern California Permanente Medical Group, USA)
🗓️April 23, 2024 - 12:00 PM (ET, NYC)

Ceci n'est pas un myélogramme.
#hemepath #labmedicine

#hemepath IHC - CD71 in marrow. Strong staining are erythroids. Weak is AML. CD71 is transferrin receptor. All proliferating cells need iron, but erythroid need LOTS!