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What if the food you eat every day is slowly damaging your health? We’re surrounded by so many diets and endless advice that is conflicting which leaves most of us confused. So I wanted to sit down with someone who has studied and lived it for their whole life. Dr Andrew

🕰️ Is #aging driven by a programmed/programmatic mechanism, or by the unavoidable burden of imperfect maintenance? Our Nature Aging Perspective argues that aging reflects finite maintenance and reduced evolutionary pressure🧵 nature.com/articles/s4358… Björn Schumacher Alexei Maklakov

Daniel J Drucker I think one issue is that we often conflate the causes of a disease with the reverse direction of effective therapies. I am sitting next to Roy now, I suppose I could ask him!

Much needed for the community!

Mutation-induced filaments of folded proteins are inert and non-toxic in a cellular system | Molecular Systems Biology embopress.org/doi/full/10.10….

Amazing stuff as always from the Hornberger lab. As much as I love TOR, there are also many other things going on!

You don’t like your trial results. Just add a meta-analysis to the results. My take on Sensible Medicine sensible-med.com/p/rescuing-a-n… Cc Sanjay Kaul

Long overdue

Genetic impairment of ketone body signalling is a prevalent contributor to human metabolic dysfunction medrxiv.org/content/10.110… Working with our great collaborators at Pfizer we have uncovered a common genetic contributor to metabolic ill health/

Our new paper out in Trends in Molecular Medicine “Science captured by storytelling: the oxidative stress narrative” DOI: authors.elsevier.com/a/1lt2w5Eb1BhM…

Truly exciting work done in Roger’s group!

my latest investigation for Consumer Reports is based on months of reporting and 60+ lab tests of leading protein supplements we found that most protein powders and shakes have more lead in one serving than our experts say is safe to have in a day — some by more than 10 times !

Consumer Reports nearly all the plant-based products we tested had elevated lead levels: vegan powders had 9x as much lead as dairy & 2x as much as beef dairy-based powders had the lowest levels, but half were still too contaminated for safe daily use how could this be? well...

In which folk become aware that it’s always been Opinion Based Medicine (OBM). It just depends on what that opinion is informed by: x.com/dnunan79/statu…

This paper may win the 2025 Y-Axis shenanigans award 👇🏻

La grasa corporal se comunica con otros órganos. Guadalupe Sabio de #CNIOStopCancer liderará un consorcio internacional que ha recibido una ayuda #ERCSyG de €10 Mio. para investigar cómo afecta a la salud el mal funcionamiento de la grasa. European Research Council (ERC)  bit.ly/3LixCtt

So happy to see this paper of ours online. Special thanks to Ryan Montalvo and RJ for the true team work. sciencedirect.com/science/articl…

Ozempic exists because scientists studied Gila monster saliva. The exact kind of basic research this Administration would have cut without hesitation. Breakthroughs like this happen only if we choose to fund science even if the outcome is impossible to see at the start.

What a structure!

How is timely and accurate sister chromatid separation achieved? A process that is happening around 30-50 billion times per minute!!! in the human body needs tight regulation (to avoid cancer development...). paper: lnkd.in/eHCYuyhc comment: lnkd.in/ezyw2dxi