A RCT suggests that a 14 day treatment of enteropathy with the GLP-2 receptor agonist teduglutide may be beneficial in children with complicated malnutrition Nature Communications nature.com/articles/s4146…

Beyond mice with #diet induced #obesity is there an optimal pre-vaccination diet? Nature Microbiology nature.com/articles/s4156…

Imagine the impact on civic institutions, academia and our public and private spaces if leadership and police actually chose to enforce existing rules, regulations and bylaws. Yet many leaders are not up to the task and our civil environment is degraded time.com/6968385/google…

#Genetics and drug discovery For SGLT2i and GLP1RA directionally supportive yet drug development largely driven independent of genetic evidence #T2D #heartdisease nature.com/articles/s4158…

50% of the human #insulin expressing #islets are virtually devoid of glucagon-producing α-cells, an observation with significant implications for both experimental and clinical research Nature Communications nature.com/articles/s4146…

“Women tend to wait until they tick all 30 boxes before they first put in for an academic position”

Wiebke Arlt talks about her impressive career and work supporting women in #endocrinology as President-Elect of European Society of Endocrinology (ESE), in The #Endocrinologist : ow.ly/VPUe50Rib5I

Won’t be the last, congrats!

GLP-1 is pretty hot these days but you know you are really crushing it when you publish a paper nature about a cool brown dwarf nature.com/articles/s4158…

The developing human pancreas Diabetologia link.springer.com/article/10.100…

SURMOUNT-OSA Tirzepatide and obstructive sleep apnea investor.lilly.com/news-releases/…

LRP1 in GABAergic neurons may play a crucial role in maintaining normal excitatory/inhibitory balance, impacting memory function, and reinforcing the potential importance of LRP1 in neural system integrity Molecular Metabolism sciencedirect.com/science/articl…

Leptin resistance in DIO mice is the result of increased mTOR activity in POMC neurons and that inhibition of mTOR reduces obesity by reversing leptin resistance biorxiv.org/content/10.110…

The authors advocate that maintaining a stable pool of rejuvenating miRNAs in circulation may offer a therapeutic strategy for modulating the #aging process and mitigating its impact on overall health and well-being Nature Aging nature.com/articles/s4358…

Ongoing research suggests that stopping medication for chronic medical conditions is associated with loss of some of the previous benefits of the medicine, #weightloss #obesity
nature.com/articles/d4158…

Here the authors associate changes in circulating IGFBP1 in the glycemic physiology and #insulin sensitivity of #pregnancy Nature Medicine nature.com/articles/s4159…

Please be careful out there #weightloss reuters.com/technology/cyb…

New from Mitch Lazar An unanticipated, non-canonical activation function of NCoRs that is required for metabolic health Nature Metabolism Penn IDOM nature.com/articles/s4225…

The glucose-lowering drug metformin reduces the incidence and severity of alpelicib-induced hyperglycaemia #cancer eClinicalMedicine – The Lancet Discovery Science thelancet.com/journals/eclin…

Turns out that if tirzepatide is superior to semaglutide in a H2H study, the conclusions hold in a network meta-analysis #T2D ⁦Diabetologia⁩ link.springer.com/article/10.100…

The intersection of frailty and metabolism Cell Metabolism
cell.com/cell-metabolis…