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David Liu wins the Breakthrough Prize in Life Sciences for developing gene-editing technologies, including a "molecular word processor" that can find and replace whole sequences of DNA. His tools are already impacting diseases including cancer. breakthroughprize.org/News/91

Last night I was honored to receive the 2025 #BreakthroughPrize in the Life Sciences, reflecting the efforts of many students, collaborators, doctors, and patients in labs around the world. I hope this 4-minute excerpt can inspire when science needs public support more than ever.

Congratulations to Boston's David Liu, Joel Habener, and Alberto Ascherio — Breakthrough Prize winners at the Oscars of Science! Massachusetts is proud to be the place where lifesaving, world-changing innovation happens. bostonglobe.com/2025/04/05/bus…

Our latest on 🫀 health, 🧬, & 🤰 now out in JACC Journals #JACC ⬆️ 1st-trimester CV health strongly associates w/ ⬇️ risk of hypertensive disorders of 🤰 (HDP) overall & across levels of HDP 🧬 risk ➡️ opp to prevent 🤰 complications & long-term CVD jacc.org/doi/10.1016/j.…

A study published in Nature Genetics details a new computational framework--MESA--that uses ecological theory to map cellular diversity and spatial patterns in tissues, offering new insights into disease progression. chemistry.mit.edu/chemistry-news…

As an academic who works on tech to discover causes and cures of disease, contributing to novel drugs reaching patients has been thrilling. Thanks to @STATNews naming me to STATUS List 2025 honoring leaders in health, medicine, and science! 🧵 #STATUSList statnews.com/status-list/20…

🚨Latin American Workshop Series🚨 The Beth Cimini Lab 🔬💻 📊 from Broad Institute and Center for Open Bioimage Analysis will host a free, hands-on image analysis workshops for LATAM... in SPANISH🇪🇸 and PORTUGUESE🇧🇷!!!🎉🎊 broad.io/latam_workshop… Deadline: April 23rd, 2025

Congratulations to Anne Carpenter, PhD for being recognized on the STAT 2025 STATUS List! Very well-deserved! #STATUSList

Story by Alvin Powell on Sonia Vallabh and Eric Minikel’s very personal mission with our lab and others to develop a gene editing treatment for prion disease: news.harvard.edu/gazette/story/…. The research paper in Nature Medicine can be found below. prionalliance

So glad you were able to join us John! Broad Institute BroadMPG

We developed a new siRNA drug candidate for prion disease, a Broad Institute / RNA Therapeutics Institute collaboration. We now have an open IND meaning FDA has given us permission to start first-in-human trials. Work remains before trials can launch. The full update: cureffi.org/2025/04/14/ope…

Antibodies that suppress tumor growth in a challenging cancer! This issue’s cover features work by William R. Sellers & team Broad Institute on the identification of biparatopic FGFR2 antibodies that are effective against FGFR2 fusion-driven cholangiocarcinoma.

Join us May 13 at 6PM ET in Cambridge, MA (or online) for a Broad Discovery Series × BroadIgnite talk with Ralda Nehme and Shiwei Wang, “How Brain Cells Talk to One Another.” Register: broadinstitute.swoogo.com/DiscoveryxIgni…

🔬 A new computational approach pioneered by researchers at the Broad Institute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue. See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau

On the heels of our two collaborative studies connecting clonal hematopoiesis to kidney outcomes (journals.lww.com/jasn/abstract/… & journals.lww.com/jasn/abstract/…), delighted to share our review synthesizing the evidence to-date on clonal hematopoiesis and kidney disease led by Zhi Yu

"Don't get too comfortable being comfortable." Diane Diehl’s advice for a thriving career in science: stay curious, keep learning, and talk about your goals. Her journey shows how scientists can thrive beyond the lab. 🔗:broad.io/WISDiane #WhyIScience #STEMCareers

Delighted to share my tribute to Christian Happi in this year’s #TIME100. A brilliant scientist, a relentless leader, and a dear friend—his work has transformed outbreak response across Africa, built a genomic powerhouse in Nigeria, and is inspiring a generation. TIME

Wise words from Count Me In's dedicated Director of Operations, Diane, who brings her curiosity and drive to our operations every day - helping grow and scale our patient-partnered research efforts. See more on her journey: 🔗 broad.io/WISDiane

Targeted Degradation of CDK9 Potently Disrupts the MYC Transcriptional Network by Mohammed A. Toure, Angela N. Koehler et al at Broad Institute @KochInstitute dlvr.it/TKD9Wl

Deeply honored to receive the Edgerton award and thanks to all the great and supportive people at MIT and in the lab who made it possible!