An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model: buff.ly/3w5zJJF

#Immunology

Up next in the ASCI Scientific Sessions:

Emily Wang

'Can we achieve health equity without ending mass incarceration?'

May 10, 1-2pm ET

Moderated by Susan Cheng, MD, MMSc, MPH Cedars-Sinai Academic Medicine

Free and open to all!

Register: buff.ly/4d8VsBk

T antigen–specific CD8+ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinoma: buff.ly/4d4z0Jz

DTU
#Immunology #Oncology

#AuthorsTake : Prolonged transplant survival in preclinical models: buff.ly/49Q3pbq

Article: buff.ly/4a1M9Rc
Video: buff.ly/44admQ5

Leonardo V. Riella Mass General Kidneys
#Immunology

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia: buff.ly/49LBr0x

Richard Moriggl Vetmeduni
#Genetics #Hematology

CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4: buff.ly/3xWp2tn

Northwestern Feinberg School of Medicine

#Immunology #Metabolism

#AuthorsTake : A glycolysis/HIF1a axis in promoting G-MDSC activity and biofilm persistence during PJI is important: buff.ly/49OqWcU

Article: buff.ly/49OdA0m
Video: buff.ly/4d3x441

Tammy Kielian University of Nebraska Medical Center
#Immunology

Complement C3 and marginal zone B cells promote IgG-mediated enhancement of RBC alloimmunization in mice: buff.ly/3Qi8J0C

James Zimring UVA School of Medicine
#Immunology

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis: buff.ly/3U6ffZ9

Michigan Medicine
#Development #Therapeutics

#Commentary :
Oncotherapy resistance explained by Darwinian and Lamarckian models: buff.ly/3Q5qjVk

Yogen Saunthararajah Cleveland Clinic

Related article: buff.ly/3w6wth7

#Commentary :
VHL governs m6A modification and PIK3R3 mRNA stability in clear cell renal cell carcinomas: buff.ly/3JkPJuz

Boyi Gan, PhD MD Anderson Cancer Center

Related article: buff.ly/3JnBeGf

#Review : Capillary malformations: buff.ly/4aF1t6W

Elisa Boscolo University of Cincinnati

This review is part of JCI's latest #Review Series: buff.ly/49FhecX

Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency: buff.ly/3w6wth7

Amit Verma Joshua Brody, MD Albert Einstein College of Medicine - Official Icahn School of Medicine at Mount Sinai NIH
#Oncology

Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis: buff.ly/3JnBeGf

Qing Zhang UT Southwestern Medical Center
#Oncology

#Review : Central conducting lymphatic anomaly: from bench to bedside: buff.ly/3xOuDSv

NIH

The review is part of our latest #Review Series: Vascular Malformations: buff.ly/49FhecX

Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models: buff.ly/49BwQhr

DBT-NII
#Oncology

#ReviewSeries :
Infantile hemangioma: the common and enigmatic vascular tumor: buff.ly/3Jm2Uvg

Annegret Holm Joyce Bischoff
Boston Children's Harvard Medical School

JCI's latest #ReviewSeries : Vascular Malformations: buff.ly/49FhecX

Series editor Miikka Vikkula

This series will span hemangioma, hereditary hemorrhagic telangiectasia, lymphatic abnormalities, cerebral small vessel disease, capillary malformations, and more..

100th Anniversary #Viewpoints :
Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation: buff.ly/49xpuvz

Dana-Farber Masonic Cancer Center, University of Minnesota

#Cover :
Mechanisms underlying mitotic and chromosomal defects in myelodysplastic syndrome: buff.ly/3Ui3fFz

#Image : artistic portrayal of ectopic ONECUT3-mediated dysplasia and mitotic defects; Credit: Yingwan Luo and Hongyan Tong

#Hematology