Can we non-invasively target a network identified by DBS to be potentially effective for Parkinson's? You bet we can and Goede, Horn and colleagues show us the path Movement Disorders Journal in a new prospective, randomized, double-blinded, crossover trial in 21 folks. …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

In a short randomized trial, tDCS targeting a DBS-implicated network improved PD motor features compared to sham stimulation. 11 participants underwent DBS for clinical purposes & improvements with tDCS in the trial correlated w/ motor improvement with DBS loom.ly/Fu7Dya4

One of our participants kindly shared their firsthand perspective of working with us on developing real-world adaptive deep brain stimulation for Parkinson’s Disease in this insightful article The New York Times. nytimes.com/2024/08/19/hea…

DBS Think Tank XII starts tomorrow in Gainesville, FL! Tune in at 12:50pm EST for a welcome and opening remarks from Michael Okun and Kelly Foote The first session moderated by Simon Little starts at 1pm EST If you have not registered virtually, go ⬇️ ufl.zoom.us/webinar/regist…

Can we use DBS evoked potentials to guide programming? Bahne Bahners presenting DBS Think Tank suggests we’re getting close! netstim Center For Brain Circuit Therapeutics

(1/12) Our brain network study of religious fundamentalism is out in PNAS. We identified brain networks associated with religious fundamentalism and found shared neuroanatomy with lesions linked to confabulation and criminal behavior: pnas.org/doi/10.1073/pn…

Congratulations for graduating your PhD with summa cum laude, Dr. Bassam Al-Fatly – very well deserved and it has been a real honor and pleasure to co-mentor you! Bassam’s works including three first-authorships in Brain and many new innovations: scholar.google.com/citations?user…

Merging connectomics, network models and physiology? Yes please! Bahne Bahners drops the ‘mic’ in his junior award winning talk #mdscongress on how DBS works; how we can use this information to optimize DBS programming. ⁦Lead-DBS⁩ ⁦Andreas Horn⁩ ⁦⁦Michael Fox⁩

Super proud of Bahne Bahners for representing the lab & Center For Brain Circuit Therapeutics at MDS and for this fantastic award that led to a talk in front of 4000 dear colleagues & to being featured in the MDS podcast recently! Very well done Bahne and very well deserved!! 👏👏🎉🎉🥳🎊

Mass General and Harvard Medical School Investigator Gary Ruvkun, PhD, has won the 2024 The Nobel Prize in Physiology or Medicine. He is honored for his discovery of small regulatory RNAs. Congratulations! Learn more: spklr.io/6019vzIW

🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – each time asking the patient to perform motor tasks to see how things improve. Could we use DBS-#evokedpotentials to guide programming?doi.org/10.1101/2024.1…

Using this #dryEEG setup, we recorded DBS-#evokedpotentials in 58 hemispheres in people with #Parkinson’s disease and computed a model which represents the optimal DBS-evoked #responsepattern associated with maximal DBS improvements

Once defined, we can now use this #pattern to estimate #DBSoutcomes in #unseen patients. Would the model be able to identify the optimal DBS contacts?🥁🥁🥁 Indeed: in all of the five cases tested, the model selected the optimal DBS contact correctly!🥳

Excited to share our preprint on a new approach using DBS-evoked potentials to streamline DBS programming! Big thanks to Bahne Bahners, Andreas Horn, and all the coauthors! Follow this thread to learn more! 👇 netstim Center For Brain Circuit Therapeutics Charité - Universitätsmedizin Berlin

Can we use a convenient dry-EEG setup to program DBS electrodes? Bahne Bahners & Lukas Goede say yes – tweetorial below 👇👇

Excited to be recognized with the Brain Stimulation Elsevier Early Career Award 2025! Big thanks go out to the fantastic individuals in my lab without whom none would be possible! See you in Kobe – who else is coming? Center For Brain Circuit Therapeutics netstim elsevier.com/events/confere…

Very well deserved! Huge congrats! Very happy to be part of the netstim team under your fantastic guidance, Andreas Horn!

How close are we to at home brain stimulation? Important positive trial of home tDCS for depression just out in Nature Medicine.

I had a wonderful conversation with Shan Siddiqi @shansiddiqi.bsky.social today about bringing human brain connectomics to clinical practice in psychiatry. Tune in for the latest & greatest updates on TMS, depression, PTSD, causality and more! 👇👇 stimulatingbrains.org/61-shan-siddiq…

You can now find me at Bluesky: lukasgoede.bsky.social – come follow along as I transition over!