Babak Razani, MD, PhD Laboratory
@razanilab
Razani lab @ Center for Immunometabolism cim.pitt.edu, U. of Pittsburgh studies macrophages, autophagy-lysosomes, nutrient signaling in metabolic disease
ID: 1222213330900832256
http://www.razani.org 28-01-2020 17:43:54
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Congratulations to our team member, Dr. Xiangyu Zhang Xiangyu Zhang, Assistant Prof. PittDeptofMed Vascular Medicine Institute & Core Director of Center for #Immunometabolism: Got DOUBLE awards this week 😱 (American Heart Association Career Development Award & PLRC P&F Grant). Sky's the limit 💪
Herculean effort by @Polash_23 diwanlab_wustl & team in Journal of Clinical Investigation showing role of CRYAB & #proteinaggregation in #heartfailure, ischemic #cardiomyopathy. This is beyond role in genetic CM. Congrats also on cool cover! Happy to have collaborated with you over the years 🤝
Lots to like about work of Greg_Steinberg lab in Nature Metabolism on #adrenaline stimulating #adipocyte #lipolysis (via ATGL) to activate #macrophage #GDF15 action on brain centers for #anxiety. Adipose-immune-brain axis also relevant to metabolic disease. nature.com/articles/s4225…
Congratulations to Carlos Cosme (Carlos Cosme Jr.), Pitt/CMU MSTP student in Babak Razani, MD, PhD Laboratory Vascular Medicine Institute for winning this year's Monga Family #Cardiovascular Research Award at #Pathobiology25 #ASIP2025 👏🏼👏🏼
Timely review of #precisionnutrition as strategy in #CVD #metabolism disease therapy in Nature Medicine by Marta Guasch, PhD Jordi Merino & colleagues. Note that uncovering mechanisms linking nutrients to cellular signaling true power of precision #nutrition. nature.com/articles/s4159…
Look who got his 1st corresponding author paper in Journal of Investigative Dermatology on #tcell MyD88/A20 & psoriatic #arthritis? Congrats Dr. Bahram Razani Bahram Razani, Dermatologist-Scientist extraordinaire UCSF School of Medicine. Best wishes as you setup the "other" RazaniLab💪😁 sciencedirect.com/science/articl…
Bonanza of cool papers recently on curious BMP #lipids only found in #lysosomes, discovery of degrading enzyme PLA2G15, and role in physiology & disease by labs of Judith Simcox PhD in Cell Metabolism and Monther Abu-Remaileh in nature. nature.com/articles/s4158… cell.com/cell-metabolis…
Check out our new commentary on #leucine and role in #CVD #atherosclerosis via #mtor #autophagy. Spearheaded by Xiangyu Zhang, Ali Ajam, MD & Babak Razani, MD, PhD Laboratory team we discuss next steps in limiting leucine's damage to the #macrophage & the atherosclerotic plaque. tandfonline.com/doi/10.1080/15…
Blocking #CD47 has emerged as promising therapy in #CVD. Check out work in Circulation by Zhen Guo of Ali Javaheri lab identifying CD47 in #cardiomyopathy #heartfailure induced by doxorubicin & targeting it as novel therapy. Great partnering with you on this. ahajournals.org/doi/10.1161/CI…
LIPA locus #SNP (#Lysosome Acid Lipase gene) long known as #CVD risk. Cool work by Fang Li of Hanrui Zhang lab in European Society of Cardiology Journals uses high-tech functional #genomics to uncover mechanism backed by mouse model. Thanks for including us in the journey. academic.oup.com/eurheartj/adva…
Congrats Dr. Bahram Razani (Bahram Razani) on the official lab launch UC San Francisco UCSF School of Medicine. Looking forward to seeing Great things from the "other" Razani Lab! 😁
Nice way to close summer 2025 for Babak Razani, MD, PhD Laboratory and also celebrate our summer students from Vascular Medicine Institute VUE Program and PittDeptofMed University of Pittsburgh School of Medicine Dean's Summer Research Program 🎉