Many thanks to HIRN dkNET NIDDK NIH HRHR program JDRF for their support; our collaborators Vignali Lab Mark Anderson Jishnu Das Paul G Thomas

Nick Borcherding Rahul Satija for analysis tools

And a huge thanks to our editor Madhura Mukhopadhyay at Nature Methods !

🧵5/5

ISMB is the premier computational biology conference, and we will have a great mix of invited and contributed talks in this session.
It is not too late to submit abstracts for talks or posters, deadline this Friday April 19.

Happy to co-organize Special session on Computational and Systems Immunology at #ISMB2024 with Ferhat Ay Jishnu Das Hatice Ülkü Osmanbeyoglu .
Please join us Tue July 16 in Montreal!

iscb.org/ismb2024/submi…

Congratulations to Ariadna Soto receiving the 2024 AAI Intersect fellowship and amazing Co-PI mentor Jishnu Das to study protist immune interactions. Also congrats to Elaine Kouame PhD (she/her) ;Laura Rachel Gottschalk and others #ProudPI #WomenInScience
aai.org/Careers/Fellow…

Thanks Nature Methods for highlighting our work! Cell segmentation is moving forward fast Rita Strack 🔥🔥🙌🙌

What would happen if you got vaccinated against the same antigen over and over again? In The Lancet Infectious Diseases, we now report on a hypervaccinated individual from Magdeburg (HIM) who received 217 vaccinations within 29 months against SARS-CoV-2. 👇 1/19 thelancet.com/journals/lanin…

Thanks a lot Nature Methods for highlighting SLIDE, our flagship #ML approach to identify significant latent factors from multi-omic datasets. Across a range of biological contexts, these latent factors provide inference beyond prediction.

Read the associated Research Briefing here:
nature.com/articles/s4159…

🔬 Exciting News! Our manuscript, 'scGPT: toward building a foundation model for single-cell multi-omics using generative AI' is now finally published in Nature Methods (@NatureMethods) 🎉 !!!

(Re-)Introducing scGPT: A transformative foundation model engineered for single-cell

Thanks to Nature Methods for highlighting our SLIDE paper. SLIDE can accurately predict a range of phenotypes from cellular to organismal. It also provides inference beyond prediction of 'hidden states' (latent factors) driving these phenotypes (2/2). nature.com/articles/s4159…

Flagship #ML paper from my lab now out in Nature Methods. SLIDE, an interpretable latent factor regression approach, has unique statistical guarantees. Can analyze #multiomic datasets (bulk, sc, spatial etc) to provide inference beyond prediction (1/2). nature.com/articles/s4159…

Diwali and Kalipuja fusion celebration with Jishnu Das
Wishing everyone a happy Diwali filled with happiness and prosperity!
#Diwali2023

If you're at #TropMed23 come see us at our 2 oral presentations - on TB & Schistosomiasis - or 2 posters - on Onchocerciasis & Leprosy. Updates from collaborative work with Jishnu Das Jessica Fairley, MD, MPH and collaborators Emory University CDC & UFJF Brazil.

Was a pleasure to co-moderate the 'Machine Learning for Biomedical Applications' session today at #BMES2023 Biomedical Engineering Society together with Jishnu Das. Fantastic lineup of speakers and amazing questions by the audience! The future is bright for machine learning in biomedicine! 🤖🧬💊

2023 peace laureate Narges Mohammadi is a woman, a human rights advocate, and a freedom fighter. This year’s #NobelPeacePrize also recognises the hundreds of thousands of people who have demonstrated against the theocratic regime’s policies of discrimination and oppression

Excited to share that I have been named the next Chair of the Department of Immunology at Pitt! We have a fantastic department and immunology community here and I’m honored to have the opportunity to help it grow!

“For the 20 years that we worked together before anybody knew about us or cared it was literally the two of us sitting side by side at a bench and working together.

Usually at 3 or 5am we would be emailing each other with new ideas.”

- 2023 medicine laureate Drew Weissman on

One Job, One salary. Many Hats.

Our paper describing a #MachineLearning approach to characterize cell-intrinsic and cell-extrinsic circuits underlying #scleroderma severity is now online in ACR_Journals Arthritis & Rheumatology - onlinelibrary.wiley.com/doi/10.1002/ar…

Stability and heterogeneity in the antimicrobiota reactivity of human milk-derived immunoglobulin A. A new study from Chelseá Johnson-Hence, Timothy Hand HandLab UPMC Children's Hospital of Pittsburgh and colleagues: bit.ly/3NWpXyy

Kathyayini Gopalakrishna MBBS PhD (she/her) Darren Bodkin Ansen Burr Jishnu Das