🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

📢 Thrilled to see this amazing study from a wonderful collegue and dear friend, Aura Muntasell, from HMar Research Institute and Universitat Autònoma de Barcelona finally published in Nat Immunology🔝🥳. they describe a new strategy for improving NK cell-based cancer immunotherapy!

Congrats to the 6th Waggoner Lab PhD student Alex Feldman on his dissertation defense!

Really Rapid Review of #CROI2025, which was a very strange conference given the current state of things. But still plenty of good content. Enjoy! blogs.jwatch.org/hiv-id-observa…

In chronic hepatitis B patients continue to test positive for viral components. Chloe Thio Ashwin Balagopal & team Johns Hopkins Medicine now show how the main source of hepatitis B surface mRNAs shifts with treatment: jci.org/articles/view/…

Our new #preprint on NK cell engineering is out! biorxiv.org/content/10.110… Using #CRISPR activation screens, we found a programmable mechanism to mobilize NK cells to breast cancer tumors by engineering these cells to express orphan and metabolite-sensing receptors. (1/11) The

Thank you Lefteris for inviting Dr. Harmit Singh Malik for a talk at Emory University! Honored to have a great scientist, mentor and educator visiting us!

Excited to see this out; nicely summarised by Mayo Florida AutoImmune Neurology Group. It’s a privilege to work with such great collaborators. I’m excited to now be applying these principles to cancer, with the aim of finding better biomarkers and treatments for one of the toughest challenges: brain cancer.

CMV is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade nature.com/articles/s4159… Nature Medicine Gusztav Milotay

Online now: Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies dlvr.it/TKM1jH

Paradoxical link of HLA-B∗35 to posttreatment control of HIV in combination with Bw4 and C2 KIR ligands favoring education of NK cells Asier Saez-Cirion cell.com/med/fulltext/S…

Adaptive NK Cells Exhibit Tumor-Specific Immune Memory and Cytotoxicity in Ovarian Cancer aacrjournals.org/cancerimmunolr…

Review: Peptide-specific NK cell receptors Malcolm Sim academic.oup.com/ooim/article/6…

T cell exhaustion limits antiviral response. Xu et al. Tsinghua University show that targeting BCOR & ZC3H12A potently enhances the stemness & functionality of CD8 T cells in chronic viral infections, reversing T cell exhaustion and improving antiviral immunity. hubs.la/Q03lfG4y0

BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells Journal of Experimental Medicine rupress.org/jem/article/22…

Delighted to be hosting the next KIR workshop in Oxford next year. Please save these dates if you're interested. More details to follow.

The innate power of NK cells in cancer therapy MalmbergLab Nature Medicine on Katy Rezvani, M.D., Ph.D trial nature.com/articles/s4159…

A promising phase 1 trial in patients with refractory #Hodgkinlymphoma underscores the potential value of allogeneic natural killer (NK) #celltherapy guided by NK cell-specific engagers. News & Views from Karl-Johan Malmberg, Ebba Sohlberg nature.com/articles/s4159…

#NEWS📰 Study backs early hepatitis B treatment—even without liver damage In a major #ClinicalTrial across #SouthKorea and #Taiwan, researchers found that starting #antiviral therapy for #hepatitisB early—REDUCED the risk for #LiverCancer. 📚Read more: ow.ly/gcIZ50W1yqk

Targeting lactylation reinforces NK cell cytotoxicity within the tumor microenvironment Nature Immunology nature.com/articles/s4159…

NK2026 in Italy September