Proud to share this study - entirely conceived and carried out by Samantha Sedor - on CDAN1, an essential but enigmatic protein that sequesters and inhibits multiple copies of the histone chaperone ASF1! biorxiv.org/content/10.110…

As tools to map RNA modifications advance, a major question becomes: what do individual sites do? Our new pre-print suggests a single, strategically acetylated tRNA nucleobase acts as a sentinel for cellular stress in mammalian organisms. biorxiv.org/content/10.110… 1/n

Super excited to share a preprint from my postdoc in the Rabinowitz lab on how metabolism changes during viral infection biorxiv.org/content/10.110…

1/Out today @nature, a paper from Divya Bezwada and DeBerardinis Lab Children’s Research Institute at UT Southwestern about metabolism in human clear cell renal cell carcinoma (ccRCC). Divya identified an unexpected metabolic change that allows these tumors to metastasize. 🧵below.-RJD nature.com/articles/s4158…

Glad to finally see this paper online. Using observations in humans and functional data in mice, we demonstrate that mitochondrial complex I is both necessary and sufficient for efficient kidney cancer metastasis. DeBerardinis Lab 1/ nature.com/articles/s4158…

Excited to share I will be joining Fred Hutchinson Cancer Center this fall as an Assistant Professor in Human Biology. We will investigate the metabolism of microbes that drive human diseases from infections to cancer. Recruiting soon, so stay tuned. Thanks to Emily Balskus MVH Lab Brigham & Women's Pulmonary and Critical Care.

Today in Cell we report evidence for a covalent linkage between small RNAs and N-glycans via acp3U Work by Yixuan (Axe) Xie Peiyuan Chai +collab w/Ben Garcia | HSCRB Excited to accelerate more work related to glycoRNAs in many new contexts. doi.org/10.1016/j.cell…

nature.com/articles/s4158… Excited to share new work form our lab led by Shinya Imada and Saleh Kwaled demonstrating how a post-fast refeeding drives stem cell mediated regeneration via polyamine metabolites. The work would not have been possible without our great collaborators

I’m incredibly excited to share my postdoc work in the Fujimori Lab UCSF, in collaboration with James Fraser (A$AP J), Stirling Churchman, & the Takeuchi-Tomita lab!!!! We usebiochemical & structural approaches to investigate mitoribosomal inhibition by antibiotics 🧵 1/n doi.org/10.1101/2024.0…

Very proud of this important work on how thyroid status impacts the brain and behavior. Led by postdoc Dan Hochbaum who assembled quite a team urldefense.proofpoint.com/v2/url?u=https…

Adding a new piece to the puzzle: O-glycosylation contributes to mammalian glycoRNA biogenesis Lead by Jennifer Porat, Chris Watkins and Chunsheng Jin, finding evidence for O-glycoRNAs enabled by genetic KOs, rPAL labeling and O-glycomics bioRxiv biorxiv.org/cgi/content/sh…

Very excited to share our latest paper out today Nature Metabolism showing that #mitochondria transfer and transplantation may reduce the morbidity and mortality of #LeighSyndrome, a fatal mitochondrial disease with no effective therapies. dlvr.it/TCjPl6

🚨 TWITTER!! 🚨 Our Dept is recruiting junior faculty! Please RT and share in your circles 🙏🏼😊 This is a broad search in GI patho/physiology. But, pancreatic cancer researches, do take note! Contact Shah Lab or Lyssiotis Lab with questions 🤝

In our new paper out today nature.com/articles/s4158…, we started with a simple hypothesis - inspired by work on IL-4/IL-13 from Brian S. Kim - that an innate immune cell might control sensory neuronal detection of allergens via a secreted factor. (1/11)

We look forward to ASolmonson's talk at the UTSW New Faculty Research Forum on Sept 24!

1/I’m honored and excited to start a new role UT Southwestern Medical Center, as Director of the Eugene McDermott Center for Human Growth and Development and Center for Human Genetics. -RJD

I am honored and thrilled to take on the role of Division Director for Genetic Medicine VUMC Department of Medicine! As a junior faculty member, I benefited tremendously from mentorship and support from Nancy J Cox. I look forward to paying it forward Vanderbilt Genetics Institute!

Just in time for #ChildhoodCancerAwarenessMonth, the Voit lab is hiring! We looking for interested and interesting post-doc candidates to join our team UT Southwestern Medical Center focused at the intersection of hematopoiesis, cancer biology, and gene therapy. tinyurl.com/Voit-lab-postd…

Excited to share our latest preprint, led by Dr. Monika Olahova Winter Rachel Guerra & Jack Collier in collaboration with the Wittig lab & Pagliarini Lab biorxiv.org/cgi/content/sh…

🔥 We’re hiring! 🔥 Curious how cells adapt to the ever-changing environment? Our lab dives into oxygen sensing, vitamin metabolism, and beyond. We're looking for bold postdocs and staff scientists to push the boundaries! Join us!🔍🚀 #O2 #OxyJainLab #Vitamins #JoinOurTeam