Christoph Kuppe
@KuppeChristoph
Professor @RWTH, Nephrologist, Emmy Noether Group Leader. #CKD #glomerulus #FSGS #Heart #spatial multiomics.
ID:949520725437767680
http://www.kuppelab.org 06-01-2018 05:59:17
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Next Tuesday at 2024-04-16 18:00 CEST will be another community meeting!
Doron Haviv will talk about about ENVI, a deep learnining based variational inference method to integrate scRNA-seq with spatial data. For more information, check here: github.com/dpeerlab/ENVI
Nectin-4—drug conjugates (in metastatic urothelial carcinomas): The right drug for everyone?
Happy to talk about current evidence to use Nectin-4 status to predict Enfortumab vedotin response in met. UC at #EAU24 in Paris European Association of Urology (EAU) !
Very interesting Session on saturday about
Our 30-color DNA-PAINT is out in Cell! So happy and proud to be part of this amazing team Jungmann Lab 🤩 congrats Eduard Unterauer and all co-authors!
The blueprint for #AI -driven drug discovery is here. FierceBiotech looks at Insilico's latest paper in Nature Biotechnology on its lead AI-designed #drug candidate for an AI-discovered target -- TNIK -- and what it means for the industry. fiercebiotech.com/research/insil…
It's out! A new Nature Biotechnology paper reveals how we used our #AI platform to find a promising target for fibrosis, TNIK, & designed a novel drug INS018_055, to treat the lung disease #IPF , bringing it all the way to PHII, w/ 300GB of data & a custom GPT.
nature.com/articles/s4158…
📣Excited to share our latest publication in Expert Review of Molecular Diagnostics 'From biochemical markers to molecular #endotypes of #osteoarthritis : a review on validated #biomarkers '🥳Check it out at doi.org/10.1080/147371…
🎉 Happy to share our first 📜 2024!🔬 Our review article in Genome Medicine on the innovative use of spatial multi-omics. Discover how these technologies are unlocking new understandings of cardiovascular disease. 🚀rdcu.be/dwnVi Uniklinik RWTH AC Springer Nature RWTH Aachen
🧬🔭Sounding an Alarm over Spatial Biology #SpatialBiology #InnovationNotLitigation
genengnews.com/topics/biopers…
How can #DataScience incorporate #LLMs into its practice and education? We discuss this in-depth in a new paper in Harvard Data Science Review Harvard Data Science Review hdsr.mitpress.mit.edu/pub/pqiufdew/r…
We show how #ChatGPT can simplify common data-wrangling, analyses + viz. In turn, data scientists need
Important study on the heterogeneous expression of NECTIN-4 in UC Markus Eckstein 🔥👏 Membranous NECTIN-4 enriched in luminal UC! No significant association to FGFR3 mut, PDL1 status or OS!
We currently overestimate NECTIN-4 expression in UC!!! OncoAlert UroToday.com Top Biomedical Science
Very nice to see PILOT featured at the cover of MSB! Thanks SciStories LLC for the very nice design!
Want to hear about the latest updates/new techniques in single cell and spatial genomics? Check out my lab's eighth annual Single Cell Genomics Day on March 29. Keynotes from IdoAmitLab Jason Buenrostro and Xiaowei Zhuang. Please RT/spread the word! satijalab.org/scgd
NECTIN4 amplification predicts response to Enfortumab vedotin in mUC! It occurs frequently across solid tumors (app. 25% of mUC)➡️potential tumor-agnostic biomarker for NECTIN4-targeting therapies! Happy to share our poster K17 ASCO #GU24 ! Markus Eckstein OncoAlert UroToday.com
Herzlichen Glückwunsch an Johannes Karges von der Ruhr-Universität Bochum! Von der Paul-Ehrlich-Stiftung
wird er mit dem Paul Ehrlich- und Ludwig-Darmstaedter-Nachwuchspreis ausgezeichnet.
forschung-und-lehre.de/karriere/nachw…