Kollias and colleagues examine FRC development during lymphoid organogenesis in gut PP: two separate mesenchymal cell lineages converge and form mosaic microenvironments that support immune cell activation and maintain intestinal homeostasis rdcu.be/cgNVz

At the border of Europe, yesterday morning. The darkness continues.

Huge effort from our “dream sc team” just out as #preprint with integrative scRNA-seq and scATAc-seq analyses across species to reveal gene reg networks GRNs driving arthritis! Thanks to Dimitris Konstanto Anastasios Liakos Marietta Armaka George Kollias and the other authors Biomedical Sciences Research Center Al. Fleming !

The challenge was strong .. but so we are! Amazing team effort! First demonstration of synovial fibroblast subsets in homeostasis and transitions to arthritogenesis. Enjoy! #arthritis @ARD_BMJ American College of Rheumatology NatRevRheumatol @RheumatologyNet @EULAR_Press biorxiv.org/content/10.110…

So proud of my PhD student Manos Aerakis who was granted a scholarship to present our studies on tumor cDC1s Keystone Symposia #InnateImmunity #ImmuneMemory AND #MyeloidCells! Many thanks to the organizers @KhaderShabaana Venizelos Papayannopoulos Claudia Jakubzick Martin Guilliams

So happy that our paper is finally out Journal of Experimental Medicine: Led by Tsoumakidou Lab Lab, we’re shifting paradigm in lung cancer immunity. Intratumoral CD4 T cells depend on antigen presenting fibroblasts for effector function and survival. Please check it out!

Site matters! Fibroblasts are presenting cancer antigens in the heart of tumors! Thank you Nature Reviews Cancer Journal of Experimental Medicine Biomedical Sciences Research Center Al. Fleming for this memorable moment!

JOIN us at the FirstInternational #AegeanConf on #MesenchymalCells in Health & #Disease Deadline 31.03.2022 TOP Speakers·TOP Science·TOP Venue #fibroblasts, #mesenchyme, #immunity, #cancer, #lymphoidorgans, #CAFs, #fibrosis Biomedical Sciences Research Center Al. Fleming More Info: bit.ly/3ievKzS

👏Congratulations to Biomedical Sciences Research Center Al. Fleming Researcher George Kollias George Kollias, for his 2nd #ERCAdG Advanced Grant! European Research Council (ERC) !!! 👉fleming.gr/impact/fleming… erc.europa.eu/news/erc-2021-…

I am of course delighted to be the lucky one amongst many deserving colleagues but GDP or % of GDP spent on science is not to blame at least for Greece! Rather, x axis should reflect % of GDP spent horizontally, not for productive research but for 'money go round' to clientele!

Good job!

After an unbelievable journey I have been awarded an #ERCCoG grant! We will study fibroblasts as cancer antigen presenting cells Biomedical Sciences Research Center Al. Fleming to build concepts and find therapies!  Grateful to my team, mentor and colleagues involved George Kollias Aristotelis Tsirigos bit.ly/ERCCoG2022Resu…

Tsoumakidou Lab Lab Biomedical Sciences Research Center Al. Fleming seeks motivated #bioscientists #bioinformaticians to join an #ERCCoG on “Perturbation modelling of #fibroblasts to build cell communication and gene regulatory networks and design novel #immunotherapies European Research Council (ERC) Info:👉 bit.ly/3YP7W94

NEW content online! The advent of immune stimulating CAFs in cancer dlvr.it/SjZH9w

Two touches are better than one🤓 Our novel concepts on immune stimulating #mesenchymal cells across tissues Nature Reviews Cancer Plus a reworked model of the “Cancer Immunity Cycle”  based on antigen-presenting #fibroblasts and the “Second Touch Hypothesis”👉rdcu.be/c5PnQ

The Tsoumakidou Lab Lab Biomedical Sciences Research Center Al. Fleming is seeking a motivated postDOC #bioscientist to join a #ERCCoG on “Perturbation modelling of #fibroblasts to build cell communication and gene regulatory networks and design novel #immunotherapies European Research Council (ERC) 📌fleming.gr/_files/jobs/Eo…

I just had an amazing day meeting with the scientists @BSCR_Fleming and learning about the exciting work being done here!! A huge thanks to Tsoumakidou Lab for organizing the visit. How anyone gets anything done with this view is beyond me 😍

Thrilled that my article made it to the Top 10 most-downloaded! Grateful for the support Nature Reviews Cancer Biomedical Sciences Research Center Al. Fleming #MustRead

@tsoumakidouLab Biomedical Sciences Research Center Al. Fleming seeks postdoc or MSc scientists with experience in immunology or computational biology to join a #ERCCoG on perturbation modelling of #fibroblasts in vivo and in silico to design cancer #immunotherapies European Research Council (ERC) 👉 bit.ly/3HQXUOh

A wonderful collaboration with the medicinal chemistry lab of Alexios Matralis and valued colleagues! First small molecule leads targeting #fibroblast activation driving chronic #inflammatorydisease and #fibrosis.