Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning collective migration during mouse anterior patterning dlvr.it/SlwFJd

Excited to announce two postdoc opportunities in our group @CRUK_BI. Come and join us! Please RT beatson.gla.ac.uk/careers/postdo…

We are looking for two computational scientists to join Xiao Fu's Integrative Modelling lab and to support their investigations into organisational principles and dynamics of the tumour microenvironment in solid tumours. Find out more: beatson.gla.ac.uk/careers/postdo…

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint elifesciences.org/reviewed-prepr…

Being a lifelong learner isn’t about taking pride in your knowledge. It's about having the humility to know what you don’t know. My top 23 insights from 2023 🧵

The only ChatGPT prompting sheet you'll ever need. Save 100s of hours & get more done. Sign up to Superhuman AI to get AI resources like this for free.

Genetic regulation of cell type–specific chromatin accessibility shapes brain disease etiology - Biao Zeng, Jaroslav Bendl, John Fullard, Gabriel Hoffman, @Panos_Roussos, et al. @sciencemagazine science.org/doi/10.1126/sc…

Excited to have the #PSYCHENCODE24 papers out. Thanks for the support of National Institute of Mental Health (NIMH) and the effort of multiple colleagues to bring this product to the finish line! science.org/toc/science/38…

Recent review article on neuropsychiatric symptoms in Alzheimer's disease highlights the vast areas still to explore and understand, aiming for meaningful improvements in patient treatment sciencedirect.com/science/articl…

The Center for Disease Neurogenomics (CDN) had a successful retreat day. The year 2024 marked the 10-year anniversary of the lab, and we have grown to 67 members. #CDN #retreat

Under the auspices of the PsychENCODE Consortium, Dr. Panos Roussos and his colleagues are changing the field with single-cell analyses of brain tissue with schizophrenia and unraveling regulatory mechanisms of brain disease. via Science Magazine reports.mountsinai.org/article/psych2…

We are delighted to share our latest findings today in nature. We describe cardiogenic regulation of sleep after cardiac injury. “Myocardial infarction augments sleep to limit cardiac inflammation and damage” nature.com/articles/s4158…

To all #ASHG24 attendees, I’ll be speaking during “Mapping the Brain in Health and Disease” session today. Come join me & hear about the population-scale single-cell cross-disorder atlas. 📍 Room 501 🗓️ Nov 6, 10:45 AM (MT)

🎉 Excited to announce preprints from the first #PsychAD package! Check out details of our work at Psych-AD.org 🧵 Found out summary of papers below👇

We introduce an open-source R package dreamlet (DiseaseNeurogenomics.github.io/dreamlet), which uses a pseudobulk approach and precision-weighted linear mixed models to identify genes differentially expressed with traits across subjects in large cohorts. #PsychAD

There are more papers on their way. Stay tuned. Find more details of preprints at Psych-AD.org

Center for Disease Neurogenomics Checkout DLPFC lifespan work from Aging team Hui Yang Tereza Clarence Madeline R. Scott, Ph.D.

Checkout DLPFC lifespan work from Aging team Kiran Girdhar Tereza Clarence Madeline R. Scott, Ph.D. #PsychAD

I’m thrilled to share one of the largest single-cell transcriptomic atlas of the human DLPFC with over 6.3M nuclei from 1,494 unique brain donors. Collaboration with Mikaela Koutrouli Nick Gabriel Hoffman Jaroslav Bendl John Panos Roussos and #PsychAD Consortium doi.org/10.1101/2024.1…

📢 Calling all Systems & #ComputationalNeuroscience researchers! The #FriedmanBrainInstitute is hiring tenure-track faculty in the Department of Neuroscience Icahn School of Medicine at Mount Sinai. Learn more & apply 👉 neuroscience.mssm.edu/docs/FacultySe… *Please retweet & share!