This is a Masterclass in how what you do, who you spend time with, and what you think impacts your cellular health and vitality. And longevity. Dr Picard fills in the gaps in understanding around mitochondria that are everywhere (ahem, especially here on X) and gives actionables!

They submitted a complex case to an AI, and it delivered... ‘It was the best possible legal document. And all done in seconds for pennies. How can any of us compete? We can’t’.

MoMA

Linear’s CEO just described the biggest shift in product team structure since Agile. For decades, product work meant: PM defines requirements → designers create specs → engineers translate to code. The middle step, translation, absorbed 70% of the time and created most of the

Today in Nature Medicine we report that AI can predict 130 diseases from 1 night of sleep🛌 We trained a foundation model (#SleepFM) on 585K hours of sleep recordings from 65K people—brain, heart, muscle & breathing signals combined. AI learns the language of sleep🧵

Today we’re bringing @Gmail into the Gemini era, making it a personal, proactive inbox assistant to help you manage your life, not just your messages. Explore the new features launching today, many of which are made possible by Gemini 3 🧵⬇️

Today’s Daily Cartoon, by Lynn Hsu. #NewYorkerCartoons

Claude for Chrome is absolutely insane with Opus 4.5 IMO it’s better than a browser - it’s the best agent I’ve tried so far

We’re very lucky to live in Ottawa. And now, new data confirms Ottawa is the most livable city not just in Canada, but all of North America. In a new quality of life study, we rate very high in almost every category, including safety, cost of living, purchasing power, commute

Winning tweet.

"What did your agents get done this week?" is the new perf review

🚨AI just invented a new way to “know” things. No effort. No struggle. Just instant resonance. 👉🏻Welcome to the Third State of Knowing. 🤔Are we evolving… or outsourcing our souls? psychologytoday.com/us/blog/the-di… #AI #cognition

Cursor is now easier to use than Figma

I’m increasingly convinced that the willingness to change your mind is the ultimate sign of intelligence. The most impressive people I know change their minds often in response to new information. It’s like a software update. The goal isn't to be right. It's to find the truth.

Glimpse of a world of fully generative interfaces. AI → JSON → UI: github.com/vercel-labs/js…

"I kind of think of ads as like a last resort for us as a business model," - Sam Altman, October 2024

Designers who can't code and coders who can't design both just became obsolete.

x.com/i/article/2028…

Do you understand what this means? Are you aware how much the world just changed? You can now run frontier intelligence on a potato Your $600 Mac Mini can now run unlimited super intelligence for free. No authoritarian AI companies can cut you off Do this immediately, no

Humans: 100% Gemini 3.1 Pro: 0.37% GPT 5.4: 0.26% Opus 4.6: 0.25% Grok-4.20: 0.00% François Chollet just released ARC-AGI-3 -- the hardest AI test ever created. 135 novel game environments. No instructions. No rules. No goals given. Figure it out or fail. Untrained humans