Intense hunt by biotech (i.e. Calico) & billionaires to promote lifespan (healthy aging). Here, a genetic study reveals the secret: avoid a heart attack! Most gene variants identified for lifespan are just common alleles *protective* for heart attack. biorxiv.org/content/early/…

I'll elaborate on this a little bit, since I feel it isn't just enough to say someone is my hero without explaining why. Daphne Koller (who I have never met in person) has had a disproportionately large impact on my life. Thread below (1)

An interesting new preprint on how to combine PRS and family history to improve disease risk prediction. By Alkes Price and colleagues. Bottom line: adding disease status of family members as indicators to logistic regression works well. Thread -> 1/14 biorxiv.org/content/10.110…

Are you a clinician/researcher interested in the pros and cons of screening IVF embryos for polygenic diseases (PGT-P)? Check out our new online risk reduction calculator. pgt-p-outcome-calculator.shinyapps.io/selectioncalc/

.Carl Zimmer's daughter enjoyed her science fair experience. It left him feeling disillusioned. bit.ly/1SMDgf7

Would be great to see some work on distinguishing between these various possibilities: joepickrell.wordpress.com/2016/04/19/wha…

Someone should write a book entitled "Causal analysis for the casual analyst"

A re-analysis of the evidence for a limit to human lifespan cdn.rawgit.com/daniel-wells/h… (re nature.com/nature/journal…)

Surprised to find a quote from Robin Hartshorne's "Algebraic Geometry" in this article on long range 3pt shooting: theringer.com/steph-curry-ba…

Young mathematicians: how should you decide whether, and if so how, to move into private-sector data science? quomodocumque.wordpress.com/2017/02/26/mat…

Ingredients in Victoria's Secret Bombshell and Ivanka Trump eaux de parfums that repel mosquitoes biorxiv.org/cgi/content/sh… #bioRxiv

New from our Team: GWAS & HLA region fine-mapping identify susceptibility loci for common infections go.nature.com/2f8vguB Nature Communications

Congrats to Bernd Sturmfels, past ICERM scientific board member, who will receive the 2018 George David Birkhoff Prize in Applied Math from the AMS. #appliedmathematics #appliedalgebraicgeometry ams.org/news?news_id=3…

My latest work w/ 23andMe Research Alastair Noyce on the Parkinson's disease phenome! Associations between PD and 840 survey-based phenotypes. Replicated 32 known associations and highlighted some potential risk factors (migraine, OCD, allergies, anemia). biorxiv.org/content/early/…

Deep learning, min hashing, assemblies oh my! If you're interested in such topics, join us hexagonbio and start adding leaf nodes to this fungal tree!

Fireside Chat with Daphne Koller (ICLR 2018). The best ICLR session IMO, discussing ML & computational biology, online free education, and women in science youtu.be/N4mdV1CIpvI

"advantage to studying polygenic risk pre-GWAS: we worked with simulated data only" #grswebinar #notatypo

Why-Because graph is what I'm calling decision trees from now on. #GRSwebinar

Our Health R&D team is looking for a scientist to create novel health products. Background in epidemiology & machine learning a plus 📈👩‍🔬 #jobs #hiring #ASHGtrainee 23andme.com/careers/400840…