What gets erased when you integrate single cell data, and can you recover it? Finally, we know what happens and how to recover the lost signals. So excited to share CellANOVA, published online today in NBT! go.nature.com/4hZnzW5

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. nature.com/articles/s4158…

The wait is over!! We are thrilled to announce that we have chosen Spatial Proteomics as 2024’s Method of the Year! 🥳 For more on Spatial Proteomics and a road map to this special issue, please see this month’s Editorial or read on in this thread. nature.com/articles/s4159…

Mille mercis à l’INSERM qui nous a accordé ce prestigieux prix🏆. Il s’agit d’une récompense collective pour les équipes de recherche et hospitalière qui travaillent sans relâche pour améliorer le quotidien des patients atteints de maladies rares. 🥳🍾🙌🎉 inserm.fr/portrait/laure…

Our most recent work out today ⁦Nature Cardiovascular Research⁩ led by Tore Bleckwehl and ⁦Sikander Hayat⁩ in collboration with ⁦Novo Nordisk⁩ ⁦Vivek Das⁩ Simon Baumgart 👇👇👇 nature.com/articles/s4416…

TET2 germline variants impair DNA repair and activate cytosolic nucleotide sensors, promoting kidney disease. It's a novel risk gene identified via GWAS integration in over 800 loci. Genomics Research Innovations, PMID:39511169, Nat Commun 2024, Nature Communications

Our spatial multi-omics technology that co-profiles five modalities is now published in Nature Methods Nature Methods! Huge thanks to Marek Bartosovic, Mingyao Li, and my amazing team, including postdoc Pengfei_Guo and PhD student Liran Mao! nature.com/articles/s4159…

New technology in The American Journal of Pathology enhances cellular and molecular insights into #kidneylesions by combining traditional histopathology and #spatialtranscriptomics spkl.io/6011fW5xz American Society for Investigative Pathology Chhavi Chauhan (CC) Ben Humphreys Isnard Pierre #molecularmicroscopy #precisionpathology

Multiomics single-cell optimal transport moscot.spatiotemporal An #OptimalTransport-based common coordinate framework to map & align #SpatialTranscriptomics with single-cell/-nucleus omics data scalable for millions of cells across multiple time points vs Tangram gimVI

[PUBLICATION] Podocyte-specific YAP activation drives crescentic glomerulonephritis via cross-talk with parietal epithelial cells. 🌙 A study from the Terzi & Pontoglio labs now out in Science Translational Medicine Science Magazine. science.org/doi/10.1126/sc…

Thrilled to share our work and truly honored to share senior autorship with fabiola.terzi ! Thanks Science Translational Medicine for publishing our work ! science.org/doi/10.1126/sc…

Happy to share our recent work: TSC-associated tubulointerstitial kidney disease. kireports.org/article/S2468-… Thanks to KIReports for publishing our work !

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Antigens in membranous nephropathy: discovery and clinical implications nature.com/articles/s4158…

Fibrosis: cross-organ biology and pathways to development of innovative drugs | ⁦Nature Reviews Drug Discovery⁩ ⁦Rafael Kramann, MD PhD⁩ nature.com/articles/s4157…

Congratulations to Ben Humphreys, Chief, WashU Nephrology, on joining the editorial board of Journal of Clinical Investigation as Associate Editor! #Nephstrong WashU Medicine Department of Medicine nephrology.wustl.edu/benjamin-humph…

Nature research paper: NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity go.nature.com/4lOZKSc

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Very proud to have participated in this amazing work showing how we can combine the strengths of multiple spatial transcriptomics technologies! Congratulations to Qiao and to the wonderful leadership of Ben Humphreys!! nature.com/articles/s4146…