🧪 St. Jude researchers and their collaborators found that yo T-ALL diagnosed in children under three years of age was extremely high-risk and enriched for genetic alterations that result in both LMO2 activation and STAG2 inactivation. Cancer Discovery | bit.ly/3L43jDm

Congratulations!!

Congrats Eileen!!

Congratulations Mathijs Sanders!! Well done!

Delighted to see this great News & Views article written by Jim R. Hughes and James Davies on our recent GAGE-seq paper Nature Genetics -- Single-cell technologies meet Hi-C. A fantastic read! nature.com/articles/s4158…

We are looking for a computational PhD student to take lineage tracing in human to the next level. Read our preprint biorxiv.org/content/10.110… and the job ad recruitment.crg.eu/content/jobs/p…

Very proud of you Dimitrios!! Well deserved! Now we have to celebrate in NYC and pursue the curation of the best food places.

My new favorite RNA velocity plot from a published paper.

Fascinating! Transcription factors and the suboptimization principle to ensure specificity. Kudos to the Denes Hnisz lab and colleagues!

A plasma proteome clock gives age and predicts the risk of 18 chronic diseases (diabetes, Alzheimer, cancer…). It’s in your veins.

Interested in non-coding alterations, large-scale genomics, leukemia? Collaboration between Charles Mullighan and Teachey labs. Genomic analysis of >1300 WGS/WTS/WES samples from T-lineage acute lymphoblastic leukemia, out now in nature nature.com/articles/s4158… Highlights (7):

Very impressive study!! Congratulations to all and particularly to the Charles Mullighan and Teachey labs for being so inspirational in better understanding and treating leukemia.

In the Spotlight: Iron: The Secret Ingredient Breaking PARPi Resistance. bit.ly/4dF9ryJ Hamed Alborzinia @angelifriedmann @uni_wue @rvz_wuerzburg

Very proud to share that my postdoc work from @mvhlab is now published Nature Metabolism! 📢nature.com/articles/s4225… See below for details…

📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT! 📷📷 jobs.rutgers.edu/postings/223546

Major effort from the lab (💪Robert Frömel), finally on biorxiv: We built 60,000 fully synthetic enhancers and measured their cell state specific activity during blood stem cell differentiation. Why did we do that and what did we learn🧵? biorxiv.org/content/10.110…

Fantastic series of seminars and you don’t even need to leave your office chair.

Looking for PhD students/postdocs for my newly opened lab at the Institute of Human Biology of #Roche in Basel. We work on human lung, liver and gut #organoids. Send email + CV + motivation letter to [email protected] with header #IHB institutehumanbiology.com

The lab manager position is filled! But we are now looking for a postdoc in my new lab INEM NECKER in Paris! Please RT !

Great news! Looking forward to seeing you around!