Online now at Cell: Illuminating G-Protein-Coupling Selectivity of GPCRs zpr.io/gSiJJ

A new anti-cancer drug that targets a common genetic abnormality has shown promise in a study of mouse and human tumours. The research, which includes the first known report of KRAS inhibitor treatment in human clinical trials, is revealed in Nature. go.nature.com/34lvW7J

My favorite papers challenge biomedical dogma. Here's my summary of the ones in 2019 that provided evidentiary shakeups (2nd annual list) [let me know the ones I missed]

Why we can’t cure cancer with a moonshot - Another masterpiece from ⁦KaelinLab⁩ ⁦The Washington Post⁩ ⁦Dana-Farber⁩ ⁦@HHMINEWS⁩ ⁦Dana-Farber News⁩ washingtonpost.com/opinions/the-p…

Sachlich, informativ und man lernt noch etwas über Epidemiologie 👍👍 podcasts.apple.com/de/podcast/das…

Everything you wanted to know about coronavirus modelling, but were afraid to ask. go.nature.com/2JLIcG5

Curious about what’s going on in submission/peer review/publication of SARS-CoV-2 studies? Me too! TL;DR, it’s NUTS. (1/7)

This is really interesting - well done! ukbonn.de/C12582D3002FD2… Any quantification available for supp fig. 2? Can someone explain at which AB dilution you talk about a specific immune reaction and when is it just random binding? Christian Drosten Hendrik Streeck

Boom 💥 😄 Nicht Nachmachen Haus sprengung youtu.be/QZwdXzudTBo via YouTube

The landscape of chromothripsis across adult cancer types | Beautiful work by Aurélie Ernst and team in collaboration with the DKTK MASTER network! ⁦⁦DKFZ⁩ ⁦NCT Heidelberg⁩ ⁦VomLaborInDiePraxis⁩ nature.com/articles/s4146…

Today our editorial on the impact of the COVID-19 crisis on life scientists was published. A huge thanks to our colleagues for contributing to the survey we conducted on the impact of COVID-19 on the daily work of biologists. genomebiology.biomedcentral.com/articles/10.11… Oliver Stegle Korbel group @ EMBL

Wichtig ☝️

The Cancer Core Europe Molecular Tumor Board Portal | Wonderful team effort led by ⁦David Tamborero⁩ ⁦Rodrigo Dienstmann_MD_MBA⁩ and Janne Lehtiö | ⁦DKFZ⁩ ⁦NCT Heidelberg⁩ ⁦Cancer Core Europe⁩ nature.com/articles/s4159…

Israel's Covid-19 end game: Lockdown + Rapid vaccination Israel is the first to enter a 3rd lockdown but is also #2 in vaccines per capita with 2.4% vaccinated and a daily date of 1.1% This strategy may end our Covid-19 fatalities by March. We modeled how this may play out >>>

Für alle, die gerne genau verstehen wollen, wie der BioNTech mRNA #Impfstoff aufgebaut ist und funktioniert, aber eher einen technischen Hintergrund haben! Lesenswert ⬇️ Selbst für Biologen spannend: komplette Sequenz von BNT162b2 öffentlich bei der WHO! berthub.eu/articles/posts…

NEW: a common response to reports of hospitals struggling this winter is "it’s no different to a bad flu season!" I’ve tracked down historical data on flu ICU admissions, including winter 2017-18, a record high. Here’s how England’s Covid winter compares to a bad flu season 📹

Interview with Virologist Christian Drosten: "I Am Quite Apprehensive about What Might Otherwise Happen in Spring and Summer" spiegel.de/international/…

Your front-row seat to my Mars landing is here. Watch how we did it. #CountdownToMars

"It's not a goal that is the goal, it's actually the path towards the goal." 2014 chemistry laureate Stefan Hell shares his best career advice for young scientists and researchers. Wishing him a happy birthday today! #NobelPrize

Laufräder für Nagetiere werden in Labors für Studien und zur Beschäftigung der Tiere genutzt. Was wilde lebende Nager mit einem Laufrad anfangen würden, wollte eine Forscherin wissen und stellte eins in ihren Garten – mit Bewegungssensor und Kamera. Dann kamen die Tiere ... 🧵 |1