It's accepted! See our article describing the context-dependent role of Lphn2's tethered agonist in hippocampal assembly. This was available on BioRxiv in Sept. 2022, but now it's in the finalized form! Jonathan A Javitch CA18240 Adher´n Rise doi.org/10.7554/eLife.…

📰Check out our latest work from @LabSkiniotis on "Time-resolved cryo-EM of G protein activation by a GPCR" that is now on bioRxiv!👀 #GPCR #cryoEM [a thread w/ videos below] (1/6) biorxiv.org/content/10.110…

Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator pubs.acs.org/doi/10.1021/ac…

So happy and honored to be part of this incredible contribution to the field, led by Valerie Panneels and Gebhard F X Schertler Ultrafast structural changes direct the first molecular events of vision nature.com/articles/s4158… Congrats all authors!

A true privilege to be a part of such an inspired interdisciplinary team. CFTR Function, Pathology and Pharmacology at Single-Molecule Resolution: rdcu.be/c8ef7

I am so honored and grateful to have been awarded the #NSFGRFP! I am incredibly thankful to the people who have helped me get to this point: Kevin Bath, Jonathan A Javitch and Caline Karam, just to name a few. [1/7]

Happy to report that we found what we believe the first ever #GPCR for neurotransmitter glycine. It is an unusual receptor - an orphan GPR158 which couples to RGS proteins instead of G proteins. Thus it is also the first ligand-regulated RGS! Check it out science.org/doi/10.1126/sc…

Announcing our publication featuring Sarah Shelby Sarah Shelby with @leventallab in Nature Chemical Biology! nature.com/articles/s4158… or rdcu.be/c8MrE TLDR: functional lipid rafts driven by membrane phase separation exist in live cell membranes, but with an unexpected twist! #lipidtime

Check out our latest work on the cryoEM structure of the Leptin receptor complex and the rational design of biased Leptin agonists, out today in Nature Communications!! Another great 🇨🇦 collab with Nathanael Caveney nature.com/articles/s4146…

Take a break from doomscrolling and relax with this dazzling video of the neurotransmitter glutamate being released into synapses, made possible by a new indicator developed by Abhi Aggarwal, Kaspar Podgorski, & team. Out in @NatureMethods: nature.com/articles/s4159… #NeuroTwitter

CryoEM structure of the human glutamate receptor heterodimer mGlu2-mGlu3 (PDB code: 8JD0) #scivis #sciart #molecularart #proteinimager behance.net/gallery/173824…

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase

Congrats Alekhya Govindaraju and all authors! Excited to read this!

Check out this very cool paper. Congrats to all!

Join us! The Gallo Lab is hiring a #postdoc to study the cellular and circuit mechanisms of impulsive behavior, focusing on ventral striatal acetylcholine and dopamine. To learn more and apply, please visit: careers.fordham.edu/postings/5399. Friends, please RT!🧠🐭 #postdocjob

Working on dopamine receptors keeps me happy. Check out our latest paper on Proximity Photopharmacology, again with @IsacoffLab and Prashant Donthamsetti. pubs.acs.org/doi/10.1021/ja…

Mitochondria doesn’t have to be mysterious and misunderstood. Martin Picard is a wizard at explaining mitochondria for all of us to understand!

Excited to see this in press. Congrats to all involved.

"Reengineering of a flavin-binding fluorescent protein using ProteinMPNN" Three designs were expressed and possessed the desired properties, including fluorescence and thermostability biorxiv.org/content/10.110…

As a PI, I’ve worked to ban the word “easy” from my vocabulary when talking about research. Nothing is easy, and the longer we’re out of the lab, the more we tend to forget this.