Do you think you would you have discovered a gorilla hiding in plain sight in your data? We found that you are 5 times less likely to do so if you have a specific hypothesis in mind. *A hypothesis is a liability* genomebiology.biomedcentral.com/articles/10.11…

Full article: Human research islet cell culture outcomes at the Alberta Diabetes Institute IsletCore ⁦James Lyon⁩ ⁦Alice Carr⁩ tandfonline.com/doi/full/10.10…

We are recruiting multiple graduate students to explore funded projects on how #Stemcell-derived LSECs gain and maintain their functions. Bring your #Cellculture #CRISPR #scRNAseq skills to fight #LiverDisease and #HemophiliaA as a #CellTherapist. ohri.ca/profile/bgage/…

How long do you delay therapeutic plasma exchange (TPE) after a dose of rituximab? This article says we should delay TPE by 72 hours. I have not been doing this. ncbi.nlm.nih.gov/pmc/articles/P…

Automated insulin delivery has been a huge step forward, but people would prefer not to have T1D and sensors and infusion sets can let them down. We need to keep pressing forward Alberta Diabetes. Great to collaborate with Shareen Forbes Sufyan Hussain Katarina Braune, MD

@nictitate and team present a new INS2A-EGFP/+;IAPP2A-mScarlet/+ hESC line providing a useful tool for tracking populations of maturing glucose-responsive hESC-derived β cells in vitro #stemcells #islets #diabetes sciencedirect.com/science/articl…

Itai Yanai How about forcing scientists to read the work and evaluate themselves, rather than letting 3 random reviewers selected by an over-worked (often young and inexperienced) journal editor decide. We should be able to make the effort for recruitment, promotion, awards

Here you can find our latest review on cellular therapies for T1D rdcu.be/dSQlT Thanks to Grattoni lab, Nicholas Mamrak & Jaime Giraldo Breakthrough T1D, Mark Poznansky Vaccine & Immunotherapy Center MGH and Paul de Vos Research UMCG for leading this effort. Enjoy reading

1 packet of urea is 7 grams of nitrogen 1 scoop of whey (protein powder) is 4 grams of nitrogen Are you using whey to treat SIADH?

Thinking about the next stage of your career in #diabetes research. What about working in Edmonton with access to human #islets and great facilities for translational research? apps.ualberta.ca/careers/postin… If you’re at #easd2024 reach out I’d love to meet and tell you more

Kidney transplant in the Myeloma patient is increasingly feasible but comprises pros and cons American Society of Onconephrology Memorial Sloan Kettering Cancer Center

Congrats Wendy Ye on receiving a Resident Leadership Award International Conference on Residency Education #ICRE2024 Incredible contributions as Lead Medical Resident in IM and Nephrology, and #MedEd research Proud to see Department of Medicine University of Toronto impact at the national level Moira Kapral

Happy to share our latest publication rdcu.be/dWuH0 Nature Communications. Congratulations to Frankie Poon and the whole group McEwen Stem Cell Institute UHN Research U of T Physiology. This was an amazing team effort, and we are thankful to editors and reviewers for their insights. A🧵

Amazing work Frankie Poon, Cristina Nostro and team! It was a lot of fun to watch this story grow!

Thrilled to share our new publication @cellstemcell "Embryonic macrophages support endocrine commitment during human pancreatic differentiation” authors.elsevier.com/a/1jw%7Ej6tu0C… Our work investigates macrophages during pancreatic development and how they support endocrine differentiation.

Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. cell.com/cell/fulltext/… 1/

LILRB3 genetic variation is associated with kidney transplant failure in African American recipients | ⁦Nature Medicine⁩ nature.com/articles/s4159…

Using iPSC-islet #organoids, the Maike Sander & Lab shows that #vasculature leads to the formation of an islet-like basement membrane that contributes to the functional improvement of SC-β cells. 🧫 Developmental Cell | bit.ly/4dIXuZC

Yesterday the 2025 #MRMSymposium ended on a high note! 🎤 We closed with a powerful keynote by Dr. Sara S. Nunes de Vasconcelos on therapeutic vascularization. 🙏 Thanks to the Stem Cell Network, Gold Sponsor & Keynote Lecture sponsor! 🏆 Congrats to our award winners!

How many gene transcripts do you actually need to diagnose rejection phenotypes after kidney transplantation? In our latest study in KIReports, we found that the answer is surprisingly low! kireports.org/article/S2468-… 1/6