Very grateful to be a part of such an incredible team. Huge thank you to Krishna Aragam and everyone else at the Broad for all of their help!

Check out our new GWAS of #CMR based LV mass measured by #AI (h/t ML4H) in >40k 👭UK Biobank. We found 12 novel loci for indexed LVM (LVMI) inc genes a/w cardiomyopathy, contractility, neurohormonal regulation Broad Institute Mass General Heart Link bit.ly/3GEoAQ3

Most popular medical advice ever: “A glass of wine per day is ‘good for your heart’!” But is it true? Sadly no… Great writeup of buzz-killing work from Kiran Biddinger and Krishna Aragam using sophisticated genetic methods to tackle this question nytimes.com/2022/03/29/hea…

Is a glass of🍷a day good for cardiovascular health? Answer very likely is a "No" Sorry. Distinguishing cause from mere correlation using human genetics Krishna Aragam Kiran Biddinger Amit V. Khera Gina Kolata NYT Health nytimes.com/2022/03/29/hea…

So grateful for the kind words, but more importantly for the incredible mentorship and for the opportunity to work with such an accomplished and inspiring team of scientists.

Just out! Our work showing insulin suppresses CVD risk in type 1 diabetes by modulating bile acids and lowering cholesterol absorption. Thread below. (1/6)

Our new study out now ⬇️ Genetic evidence links obesity to heart failure Many thanks to our coauthors James Pirruccello Shaan Khurshid Pradeep Natarajan Jennifer Ho @steven_lubitz Patrick Ellinor and as always my incredible mentor Krishna Aragam

TFE3 as a mediator of MTORC1 on SREBP and de novo lipogenesis. Congrats to The Arany lab- so great working with you guys!

Excited to finally share the results of our GWAS and multi-trait analyses characterizing the 🧬 genetic architecture of 🫀heart failure, now published in Nature Communications Thanks to Scott Damrauer and Benjamin Voight for their mentorship, and all the contributors! nature.com/articles/s4146…

Nice to see in The New York Times this nuanced discussion of the effects of alcohol intake on health, which cites our recent work led by Kiran Biddinger nytimes.com/2023/01/13/wel…

New in Nature Communications ! Our GWAS of #CMR based LV mass quantified using #AI segmentation (ML4H) in >50k UK Biobank participants. 12 loci for indexed LVM, inc genes implicated in cardiomyopathy, contractility, and neurohormonal regulation. Paper: go.nature.com/3yUSmOl

Now on medRxiv, we explore the genetic similarity between dilated cardiomyopathy (DCM) and peripartum, alcohol-induced, and cancer therapy-related cardiomyopathies (PPCM, ALCM, CCM). Led by star trio Dimitri Maamari, MD, Kiran Biddinger, and Sean Jurgens. medrxiv.org/content/10.110…

Happy to share our manuscript published today on regulation of cardiac adaptation to exercise training by PGC-1α and GDF15 in Nature Cardiovascular Research! nature.com/articles/s4416…

Today in Orli Bahcall, we report the discovery of a common CD36 variant specific to individuals of African ancestry that increases risk of DCM, and may help explain the ~2x higher rate of DCM/heart failure in this population nature.com/articles/s4158…