Do you want to run a microbial GWAS but are put off by installing a dozen different bioinformatic tools, are unsure about best practices, and how to transform the list of threshold passing variants into a neat annotated table? Then we have just the thing for you!

1/ 🧵 Thrilled to share work of Eligo Bioscience just published in nature ! We show proof of principle results of efficient base editing performed on E. coli directly in the mouse gut 🦠💡 #Microbiome #SyntheticBiology nature.com/articles/s4158…

🏫You would be working mainly with me at @IVES_livuni — our lab sits between evolutionary ecology and infection microbiology. There’s loads of exciting research going on in both of these themes, and chances for discussions with other groups eg @jojofoth Jay Hinton

Interested in phages and plasmids? 🧐 We are too! Happy to share that Beatriz Beamud and I are among the recipients of the Postdoc Seed Grants of INSTITUT PASTEUR! Can’t wait to share the results of our joint project!

New from the lab: The spread of antibiotic resistance is driven by plasmids amongst the fastest evolving and of broadest host range. Some groups of plasmids often contain antibiotic resistance genes whereas others don’t. Why? See our new preprint: biorxiv.org/content/10.110… 1/6

Today we’re excited to freely share an early-version of, perhaps, the world’s most expansive genetics dataset: Logan. #bioinformatics #petabase #genetics #genomics #openscience biorxiv.org/content/10.110…

📢 New preprint!! Combining transcriptomics, genetic engineering and CRISPRi silencing, we unveiled a plasmid-chromosome transcriptional crosstalk in multidrug resistant clinical enterobacteria - 1/10 🧵👇 biorxiv.org/content/10.110…

Thrilled to see the first review article from my lab out in advance Annual Reviews, helmed by Célia Souque: From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance annualreviews.org/content/journa…

We are looking for a PhD student or a postdoc for a new exciting study of lysogeny in cyanobacteria that includes both bioinformatic and molecular analyases. I'm now in #ISME19, so if you're here look for me and we can chat.

Excited to introduce AntiDefenseFinder - a free, open source tool that detects anti-defense systems in any genomic sequence. Available here to toggle on/off: defensefinder.mdmlab.fr. Read below for our insights into the >47K detectable systems📈 tiny.cc/8xrizz

Uni Oldenburg is starting a genomics facility, and we are looking for a bioinformatician. uol.de/stellen?stelle… The position is initially for 3 years, but there are chances of permanency after the 3 years. Please share!

Search: Tenure track Faculty Position UC San Francisco in the Dept. of Micro and Immuno, with lab space at the Mission Bay campus! We seek a creative investigator with a strong independent research plan who will be a great mentor, colleague, and peer. Job ad soon. Assistant Prof level.

📢 We are hiring a front-end web development engineer for a 10-month fixed-term contract on the HoloOligo project. ➡️ More information at sfbi.fr/emplois/offre/…. 📝 Please do not hesitate to contact us for further information.

Extremely happy to see the final published version of this study out NatureEcoEvo I really think this is one of our most important contributions to the field! nature.com/articles/s4155…

New paper from the Michelle Buckner Lab (Parisa Pordelkhaki). We tested the effects of different natural product extracts on the conjugation of AMR plasmids. Lots of great effort from ex-students Judith, Ruth, Jes, Poppy, Nivi, Dr Onalenna Neo, PhD celia and Huba Marton. microbiologyresearch.org/content/journa…

Out in Cell Host & Microbe: Conservation of antiviral systems across domains of life reveals immune genes in humans. Using phylogenomics, we traced antiphage systems in eukaryotes, predicted human homologs and validated their immune function in human cells! cell.com/cell-host-micr…

Microbial #evolution is shaped by mobile genetic elements, but many of these depend in turn on other mobile genetic elements. In this Unsolved Mystery, Eduardo Rocha and colleagues discuss the biological and evolutionary questions this raises. #PLOSBiology plos.io/3ZnXx87

Have a PhD and interested in a career in sci comm & working with preprints? Come work with us at bioRxiv/medRxiv! schooljobs.com/careers/cshl/j…