Current results do underscore the challenge posed by the continuously evolving SARS-CoV-2 JN.1 lineages and support the consideration of switching the focus of future SARS-CoV-2 vaccine updates to the JN.1 lineage.

New study. We compared the immune response of XBB and JN.1 in human infections to evaluate the necessity for #SARSCOV2 vaccine updates
Results:
JN.1 exposure induces higher neutralization against emerging mutants, including FLiRT (JN.1+346T+456L) and KP.3
biorxiv.org/content/10.110…

This:

SciELO em Perspectiva: 'Seria a nova política de acesso aberto da Fundação Bill e Melinda Gates o início de uma mudança em direção aos preprints?', por Richard Sever (Richard Sever)

Publicado originalmente no LSE Impact Blog

#CiênciaAberta #Preprint

blog.scielo.org/blog/2024/04/2…

H5N1 virus 'flying under the radar for a frustratingly long time...we’re trying to deal with something after the horse has bolted.” statnews.com/2024/04/23/h5n…

So, *preliminary* molecular clock analyses indicate that the time of the most recent common ancestor (TMRCA) of the US cattle flu clade was late December.

TMRCA of that clade and the closest relatives in birds, mid-December.

If single intro, likely between those rough dates.

1/42 New preprint: turns out MuLTEE is not only the longest running multicellularity evolution experiment (1000 days and counting), but also the longest running polyploidy evolution experiment! It reveals how whole-genome duplication (WGD) arises and impacts long-term evolution.

'If [image] issues are reported post-publication, publishers and research integrity officers may need to investigate' <- So perhaps it's better that they are identified post-publication rather than pre-publication... scholarlykitchen.sspnet.org/2024/04/23/gue…

Imagine a world where anyone, anywhere, anytime, could learn about #DNA ! 🧬 Tune into our latest podcast with DNALC’s Jason "boundless delight " Williams where we discuss the exciting possibilities of portable DNA sequencing. #WorldLaboratoryDay DNA Learning Center cshl.edu/podcasts/at-th…

Can AI rewrite our human genome? ⌨️🧬

Today, we announce the successful editing of DNA in human cells with gene editors fully designed with AI. Not only that, we've decided to freely release the molecules under the Profluent OpenCRISPR initiative.

Lots to unpack👇

Preliminary assembly of all USDA #H5N1 sequences. Thanks to Michael Worobey and others for doing the labor yesterday. Summary of first pass observations by Mike in thread.

Tldr: little diversity, suggesting one spill, but even before Feb, lots of ?s

twitter.com/MichaelWorobey…

If the papers are already on bioRxiv/arXiv, journal submission systems could be a whole lot simpler - for reviewers AND authors.

Post preprints.

AI generated summary of the AI driven gene editor OpenCRISPR.... ScienceCast sciencecast.org/casts/fb75s4pn…