Delighted to share the latest GWAS from the PGC Consortium Suicide Working Group, published today in Am J Psych! Mount Sinai Psychiatry Mount Sinai Genetics @bronfman_inst🧵below with the highlights thanks to our PGC SUI Outreach team Maria Koromina & Emily Diblasi!

Excited that our paper addressing the limited overlap between eQTLs and GWAS hits is now published in Nature Genetics! nature.com/articles/s4158…

Something big happened a few days ago. Industry leaders in the genomics fields (Regeneron, AstraZeneca, Novo Nordisk and Roche) announced their collaboration with the US's largest black medical school, Meharry Medical College, Nashville, to establish what might become the UK

Excited to be at #ASHG2023 #ASHG23! Looking forward to catching up! Check out these presentations:

Are you considering applying for PhD positions in bioinformatics or computational biology? Consider the bmi.ucsf.edu program! We are hosting an info session on Tues Nov 14 at 1pm Pacific. Register: tinv.ucsf.edu/2JUVfD. Come meet faculty and current students!

Interested in LLMs for genomic research but don't know where to start? looking for a review/survey to get started in this field? 👇👇😀 I am very excited to share that our review paper titled "To Transformers and Beyond: Large Language Models for the Genome" is now available as

This was a really wonderful collaboration with Kurt Farrell and @JohnCraryMDPHD. What really excited me about this work is how we could link 3 of the 6 PSP GWAS loci to oligodendrocytes (thanks Alexi Nott 🏳️‍🌈), one of the cell types that undergoes tau pathology in PSP!

Really excited to share this work and grateful to have been a part of this collaboration, congratulations Kurt Farrell! Very exciting findings and implications from this work.

Towfique Raj, Panos Roussos and I are very pleased to announce the release of the isoform-centric microglia genetic atlas (isoMiGA), a successor to last year’s MiGA project, now available on medRxiv as a preprint: medrxiv.org/content/10.110…

🚨First preprint from the lab🚨 Check out this new clustering method from @cathrinepet. CHOIR makes identifying biologically relevant cell populations from sc data automated, statistically grounded, and free of manual input. No more futzing around with the resolution parameter!

Our most recent work is now published at Nature Genetics. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Great collab with Guillaume Bourque lab and huge congrats to the lead author @katiearacena. Link: shorturl.at/bcdBP

Not sure what's the causal gene at your favorite GWAS locus? Ask ChatGPT :) Interesting preprint on the value of LLMs in causal gene prediction by 23andme scientists (Suyash Shringarpure et al.) "Here, we demonstrate that large language models (LLMs) can accurately identify genes likely

Day #7! So grateful to Tony Capra Capra Lab for talking with our high school students and sharing how #AI #ML can be leveraged to find causal gene dysregulation in rare diseases!

NYT connections I have received your message and will proceed to the coordinates

Heading to Denver for #ASHG24 #ASHG2024! Excited to share latest work on #RNAediting in the brain (featured session lead by Winston Cuddleston ), #APOE-stratified QTLs in microglia (TatsuhikoNaito ) & single-cell eQTLs (Jin) + splicing regulation in 10K brains (Aline Réal ,

Ecstatic to see our paper "Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing" now published in Nature Genetics with Towfique Raj Panos Roussos Friedman Brain Institute nature.com/articles/s4158…

So much to unpack here. Just so very much. Where to even begin?