
Alex Frankell
@afrankell
Research group leader @EarlyCancerCam and visiting scientist @TheCrick studying somatic evolution using longitudinal non-invasive samples such as #ctDNA
ID: 371971781
11-09-2011 21:38:17
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Join us! The Machado Lab at Cambridge University is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/


2 bioinformaticians / computational biologists / data scientists positions available in the lab CRUK National Biomarker Centre. Numerous projects available with a focus on #cfDNA sequencing analysis and ML building. A couple of days left to apply. Details below: cruk.manchester.ac.uk/recruitment/ca…


Extremely proud to see my PhD project exploring intra-tumor heterogeneity in complex karyotype AML finally out in Nature Genetics ! 🎉👩🏻🔬 They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5 nature.com/articles/s4158…

A pleasure to collaborate on this work with the outstanding Simone Zaccaria, Olivia Lucas and many others. SPRINTER is an outstanding and diligently constructed tool which I’m sure will be useful for many of other research projects.


In case you missed this from Charles Swanton - our new paper is out - we assess the clinical sensitivity for the prediction of relapse in lung adenocarcinoma from pre operative ctDNA samples provided by the added technical sensitivity of a 1800 variant WGS assay 1/3

Delighted to share our latest work exploring levels of selection operating during pre-cancerous evolution usng single-cell DNA sequencing of HSCs led by the outstanding gladyspoon cell.com/cell-genomics/…

Cancer evolution enthusiasts - you might be interested in some new data from our lab on quantifying cell divisions along evolutionary lineages in colorectal and lung cancer, published today in Nature Genetics! If so, some highlights below 👇 nature.com/articles/s4158…





📢 We're making our largest ever investment in early-career researchers Through #Springboard25, we’re investing £7.6m in 62 researchers to drive innovations that improve health and wellbeing 🌍🔬 Congrats to all 2025 awardees! 🎉 👉 bit.ly/springboard25 Department for Science, Innovation and Technology




Interested in the mysteries surrounding metastasis evolution? This perspective in Nature Reviews Cancer is my best attempt at proposing a framework that could help advance our thinking about the topic. Well. At least it helped advance my own thinking. 😅 nature.com/articles/s4156…

🥳 Huge congratulations to Early Cancer Institute, University of Cambridge group leader Tom Mitchell on his RISING STAR award from Kidney Cancer presented at #IKCSEU25 on Saturday. The award recognises talented young #kidneycancerexperts

My two NIH cancer research grants were terminated today. One involving breast cancer prevention is an “outstanding investigator award” and had received a perfect score by reviewers. How does ending lifesaving cancer research make Americans healthier? Harvard Medical School @aacr