Friday staging mini-Tweetorial!

Staging in breast cancer is a subject dear to my heart that I feel is often confusing and misunderstood. The reason is simple. On a slide, we see things in two dimensions, and therefore we are taught in two dimensions and we come to remember and

Well-differentiated Sertoli–Leydig cell tumor. Note
numerous Leydig cells in stroma.

Non-ossifying fibroma (NOF)
📈Benign, self limiting
👶🏻Skeletally immature, 2nd decade of life, M>F
🦴Metaphysis of long bones (around knee)
🩻Cortical-based, well defined, sclerotic & scalloped border, lytic, lobulated
🔬Bland plump spindle cells, storiform, scattered

WOW 🤩
70+ F, Back

Spiradenoma: focal intracellular vacuole like microluminal squamous duct differentiation.

#dermpath #dermx #pathx #skinpath ology #dermatologia #dermatology   #dermatologist #skinpath #histopathology #dermatopathologia #dermatopathology #dermatopathologist

when pretty isn't pretty
#grossing #PathTwitter #pathology #medpath #MedTwitter #xpath #pathtweetaward #placentapath #placentalpath #gynpath #pathology

Charles Herndon Tristan Rutland MBBS FRCPA IFCAP Kamran Mirza MD PhD - کامران مرزا Miruna Popescu, MD Sanjay Mukhopadhyay HemepathMD Tania Labiano Juan Carlos Garcés Swati Bhardwaj, MD Toño Navarro, M.D. This analogy makes me remember ALL the time
“Dart board analogy”

A, CD10: (+) GC, membranous.
Rule of thumb👍, all “CD” IHCs are membranous (A was CD10)
B, BCL2: (-) GC, membranous, anti-apoptotic molecules*
CD10
C, BCL6: (+) GC, nuclear, GC transcription factor, protects against DNA damage-induced apoptosis**
D, Ki67: (+) polar GC, nuclear,

Next GI Path 2nd Opinion Club ( #GIPSOC ) will be Tues AM EST (tom). Hope to see you and yr tough GI/liver cases there!
#pathology Raul S. Gonzalez, MD
Andrew Bellizzi 🇺🇦 Emma Elizabeth Furth

zoom.us/j/94185980988?…

#GUpath prostate bx:
nice example of 'microcystic' pattern prostate ca

✔️luminal accentuation (what I call 'eyeliner' sign) sometimes helpful🔬clue

pathologyoutlines.com/topic/prostate…

PathologyOutlines.com