My favourite paper published in
Gastroenterology in 2023 is shorturl.at/uBDJN
Raygoza and colleagues show for the first time that changes in the gut microbiota precede Crohn's disease onset by up to five years , supporting a causal role of gut microbiome alterations in IBD.

Huge thanks to everyone in our group who has contributed over the years, and to all who are reading and citing our papers.

'ALCOHOL-INDUCED BOWEL DISEASE', a new concept that recapitulates all the profound changes that alcohol causes in GI tract.

This article nicely reviews its clinical features and pathogenesis.

shorturl.at/gGW03 #livertwitter #MedTwitter
eGastroenterology NIAAA News

Ulcerative colitis is a lifelong inflammatory bowel disease with an increasing incidence worldwide.

A new Seminar explores current therapeutics options and the pressing need for a personalised approach to successfully treat patients: hubs.li/Q01-P1rh0

1⃣2⃣ Misconceptions about gut microbiome we are all guilty of (even the authors own up!)

I've definitely said 3⃣:
🦠10(12) bacteria per g
🦠Microbiome weighs 1-2 kg
🦠Microbiome outnumber human cells 10:1

How many #MicrobiomeMisconceptions have you?

👉🏽nature.com/articles/s4156…

Good colleagues from Department of Hepatology and Gastroenterology, AUH Aarhus Uni.hospital Simon MD Baunwall Christian Hvas just published onlinelibrary.wiley.com/share/PGPWAY7F…

Donor, patient age and exposure to antibiotics are associated with the outcome of faecal microbiota transplantation for recurrent Clostridioides difficile infection #GITWITTER

Working on the human microbiome? Alan Walker and @BugsInYourGuts highlight human microbiome myths and misconceptions in a new Perspective

nature.com/articles/s4156…

One of the most important articles on pathogenesis, prediction and prevention of #Crohnsdisease in a very long time. Hopefully this helps lead us closer to the end of #Crohnsdisease ! Congrats to Sun-Ho Lee MD PhD Ken Croitoru and the rest of the GEM team!!

Gut Microbiome Composition

Coming out tomorrow - Professor Harry Flint (Rowett Institute) and drjamesmcilroy discuss all things #microbiome and #guthealth

'What should I eat?'

Patients with IBD coming to the clinic want to know

PREdiCCt set out to find out

This Sunday at #DDW2023 I will present the initial results as a late breaking talk

If you want to learn more about #fecaltransplants and how they may be able to help people with #liverdisease please check in to #DrXandConorCure aired today on BBC1 at 10.15 British Liver Trust PROMISE Trial EASL Education King's Faculty of Life Sciences & Medicine King's College NHS King's College London King's College Hospital Research

In this weeks BiomeBite episode James provides an overview of how to improve microbiome diversity and gut health through diet and nutrition. #microbiome #guthealth #health

In episode 015 of the Inside Matters podcast, host drjamesmcilroy describes the microbiome as an orchestra producing a symphony #guthealth #microbiome #diet

1/3 Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome Nature Metabolism
The mechanism is linked to a defective production of indoles from tryptophan by the gut microbiota and insufficient AhR activation.

dlvr.it/SjMQr2

Our guest this week is Sean Lazzerini - professional boxer and 2022 commonwealth games gold medalist 🏴󠁧󠁢󠁳󠁣󠁴󠁿 #boxing #guthealth #diet #fitness

Efficacy/safety of #FMT via colonoscopy in patients with mild-to-moderate #UC
RCT
n=27 mesalazine
n=26 mesalazine +FMT

Response
4W 51.9% vs. 61.5% (p ns)
8W 70.4% vs. 84.6% (p ns)

✅well-tolerated, safe, but...

#WhatsNewOnFMT @EurFMT
doi.org/10.3389/fmed.2…

#WhatsNewOnFMT for @EurFMT
Thread: pediatric population

4. FMT for CDI in children = is FMT necessary?
n=58 referred for FMT
but ~28% did not require FMT

✅look for an alternative diagnoses in children and adults
journals.lww.com/jpgn/Fulltext/…

#WhatsNewOnFMT for #eurFMT
Thread: pediatric population

3. FMT in Immunocompromised children
n=59/9 centers
transplant/malignancy/immunodeficiency...
success rate for
1. FMT 79%
2 and more =86%
FMT-related SAE 9.5%

✅FMT in IC children = adults

journals.lww.com/jpgn/Abstract/…