
UMPhysiology
@umphysiology
The University of Michigan Department of Molecular and Integrative Physiology. Discovering how molecules, cells and organs integrate in health and disease
ID: 1027344056144281600
https://medicine.umich.edu/dept/molecular-integrative-physiology/ 09-08-2018 00:01:24
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Research from fellow Xiaoting Dai and the Longhua Guo lab in UMPhysiology published in Nature Aging shows regeneration of lost tissues in older planarians led to reversal of these age-associated changes in tissues both proximal and distal to the injury. nature.com/articles/s4358…


Beyond grateful to share that my main PhD thesis project, Targeting PIKfyve-driven lipid metabolism in pancreatic cancer (Lyssiotis Lab Arul Chinnaiyan), has just been published in nature! U-M Rogel Cancer Center Rogel and Blondy Center for Pancreatic Cancer University of Michigan Medical School Michigan Pathology Michigan Research UMich CMB


Congrats to Dr Peng Li from UM SchoolofDentistry UMLifeSciences UMPhysiology for receiving the Early Career Investigator Award in Respiratory Physiology from American Physiological Society for his work on neural control of breathing #APS2025


Congrats to my colleague Scott Soleimanpour for his installation as the Larry D. Soderquist Professor in recognition of his many scholarly contributions to Type I diabetes research. U-M Department of Internal Medicine UMPhysiology


Thanks to all the UMPhysiology PhD students who gave back to our local community by helping pack lunches for those in need who come to Hope Clinic.


Congrats to UMPhysiology PhD student and soon-to-be Dr. Ryan Neff for defending his dissertation today. Ryan has been working in the Murphy lab on the Down Syndrome Cell Adhesion Molecule in neurodevelopmental disorders


Congrats to UMPhysiology PhD student and soon-to-be Dr. Nick Urban from the Matthias C. Truttmann lab lab for defending his dissertation today. Nick's dissertation work is focused on ER resident chaperones in physiology and aging.


Finalists for the Davenport Award for Outstanding Research at our annual UMPhysiology Symposium, Chrystian Phillips,Jess Maung ,Elizabeth Kitto,Hsin-Yu Chen. Congrats to award winner Elizabeth, and proud of Hsin-Yu from my lab and all the finalists for awesome presentations.


Congrats to UMich CMB PhD student Kate M. Van Pelt, PhD ✨ for her first author paper with Matthias C. Truttmann lab from UMPhysiology published in PLOS Genetics showing loss of FIC-1 dependent ampylation slows disease in a C.elegans model of polyglutamine toxicity doi.org/10.1371/journa…

New research from Sumeet A Solanki and collaborators in Shah Lab in UMPhysiology published in American Society for Nutrition Journals #JNutr shows that a low protein diet can make colitis worse through an interaction between amino acid sensing and the gut microbiota. jn.nutrition.org/article/S0022-…


Congrats to UMPhysiology PhD student Diana Zhang UMich CMB MSTP student Wesley Huang for their co-FA paper in Nature Metabolism showing crosstalk of fibroblast metabolism and lipid ferroptosis in intestine epithelial cells worsens IBD. Shah Lab nature.com/articles/s4225…

New research from Cristian Saenz de Miera and the Elias lab in UMPhysiology published in FASEBPubs identifies a population of neurons that link nutritional state and leptin to the neurons that regulate puberty onset and reproduction in females. faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

Visiting students Jian Zhang and Yuee Zhao UM Global REACH and the Lin-Tong Lab in UMPhysiology published a paper in Advanced Portfolio News showing that hepatocyte ChREBPα protects against liver fibrosis by suppressing the activation of stellate cells advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

It’s been a decade - Happy 10 year Labiversary Lyssiotis Lab 🎉🥳 Thank you to all have who been along on the journey 🙏🏼 UMPhysiology, U-M Rogel Cancer Center, Rogel and Blondy Center for Pancreatic Cancer


Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in Nature Metabolism, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s4225… 1/n

Congrats to UMPhysiology PhD student Jess Maung and the MacDougald lab for her paper in JCI insight showing metabolic dysfunction in lipodystrophy is improved by FGF21/sTGFBR2 gene therapy, but effectiveness depends upon environmental temperature. insight.jci.org/articles/view/…


Congrats to UMPhysiology PhD student Jiaoo Su and the Affinati lab for his first author paper in Molecular Metabolism identifying a distinct subset of glucose-mobilizing VMH neurons that support physiologic glucose homeostasis. clinicalkey.com/#!/content/pla…


If you are in the Midwest and ❤️ metabolism, take note! This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference. The combined 2-day event will be Michigan Medicine, with


Another successful year for the U-M Health Frankel CVC AHA Research Summer Undergraduate Fellowship Program. Fantastic talks at the symposium! Curious and ambitious students mentored by great mentors! Looking forward to them being future scientists, leaders, and ambassadors for science!
