A novel class of dual fluorescence reporter mice developed by Rodrigo, Christian Kurts et al. (hubs.la/Q02wxY1C0) could help identify cells that produce and/or sense a given #chemokine in vitro and in vivo. Leen Hermans & O’Sullivan discuss the findings: hubs.la/Q02wxMQd0

In beautiful Genoa for the #EMBOMicroglia2024 workshop. What a fantastic few days it has been so far! Delighted to be taking part in the #MeetTheEditor session tomorrow afternoon, come along to say hello and learn more about publishing your work in JExpMed! 🏆

Loved this conversation I had with Dr. Irene Salinas Remiro! Her passion and energy is infectious, take a read here 👉 hubs.la/Q02xZTy_0

Participate in a complimentary Journal-Based #CME activity that consists of a full-text article that is free to read, a multiple-choice question test, and an evaluation/self-assessment. Our 13th CME Activity MSK CME is NOW available 👉 hubs.la/Q02xhLLj0

A culture shift to support public involvement and engagement in research. Viewpoint from Matthias Eberl Eberl Lab 👨🏻‍🔬👩🏽‍💻🔬🧫 Systems Immunity Research Institute and Sheena Cruickshank Prof Sheena Cruickshank (she/her) UoM Biology, Medicine and Health: hubs.la/Q02xgdXh0

So grateful for this opportunity and for a job that allows us to grow not only as scientists but also mentors and human beings. Thanks JExpMed Foe the opportunity to share my journey

.Dr. Irene Salinas Remiro Univ. of New Mexico uses multiple animal models to study nasal immunity and neuroimmune interactions in the olfactory–central nervous system axis in response to microorganisms. Lucie Van Emmenis spoke w/ Irene for the latest #PeopleAndIdeas ➡️ hubs.la/Q02xZTy_0

#WomenInSTEM

.Liang Wang Connor Lynch Sean Pitroda, M.D. Andras Piffko KY Ralph Weichselbaum et al UChicago Medicine Ludwig Cancer review the immune response to #radiotherapy -induced anti-tumor effects, & the combination of immune checkpoint blockade w/ radiotherapy hubs.la/Q02xZVHL0

Solomon, Song, Nathan Salomonis, Lee Grimes Lab et al. show that slow cycling and durable Flt3+ progenitors contribute to #hematopoiesis under native conditions. hubs.la/Q02x0dPw0

From our #Myeloid #StemCells and #Leukemia collection: hubs.la/Q02x0cpR0

In a recent study, Tang et al. (hubs.la/Q02w9wDH0) show that hepatic IRE1α-XBP1 signaling boosts GDF15-triggered appetite suppression and weight reduction in #chemotherapy . Adam J Rose and Sarah Lockie Monash University discuss the study: hubs.la/Q02w9zf80

Song et al. report that TIMP1 is a key regulatory factor produced by post-infection hosts that sustains long-term myeloid-biased inflammatory #hematopoiesis . hubs.la/Q02x0fYp0

From our #Myeloid #StemCells and #Leukemia collection: hubs.la/Q02x0cTC0

Happy about the map on maturation traits of our favorite cells after preterm birth and highlight their phenotypic diversity in neonatal infections.Exzellenzcluster RESIST Medizinische Hochschule Hannover The Viemann Lab Congratulation to all authors!!!

In this interview, Arlene Sharpe & Kristen Pauken Kristen E Pauken share their stories of becoming #immunologists , how they made transitions in their careers, and provide insights on the roles everyone can take to support women in science. ▶️ hubs.la/Q02vym2F0
#WomenInSTEM

Cellular #senescence : Neither irreversible nor reversible. A review from Maurice Reimann, Soyoung Lee, and Clemens Schmitt: hubs.la/Q02x07Jc0

From our #Myeloid #StemCells and #Leukemia collection: hubs.la/Q02x08Lv0

ICYMI: check out the latest #JEM_Spotlight paper + an Insight commentary picked by Xin (Cindy) Sun! 👇
x.com/10652583912144…

.Lakshmi Sandhow HONG QIAN et al. reveal the characteristics & previously unrecognized roles of skin mesenchymal niches in maintaining and protecting AML LSCs during #chemotherapy . hubs.la/Q02x0j9F0

From our #Myeloid #StemCells and #Leukemia collection: hubs.la/Q02x0chn0

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect, say Tamara Kögl, Peter Aichele, Sandra Ammann and colleagues Universität Freiburg: hubs.la/Q02x7mVm0

#Immunodeficiency #LymphocyteBiology #InfectiousDisease #FHL #STX11

The findings from Tang, Yao et al. identify hepatic IRE1α as a molecular driver of GDF15-mediated anorexia and suggest that blocking IRE1α RNase activity offers a therapeutic strategy to alleviate the adverse anorexia effects in #chemotherapy . hubs.la/Q02vSXRL0

#Metabolism

We're joining in congratulating Susan Kaech (Kaechlab (Sue Kaech)), a Salk Institute Professor Salk Institute and a JEM Academic Editor, for her 2024 Mentorship Award at International Cytokine & Interferon Society International Cytokine & Interferon Society (ICIS). JEM is proud to work with Susan! hubs.la/Q02xrNbF0

Inoue, Kurosaki Osaka University et al. show that an augmentation of BCR signaling in GC B cells by inducible depletion of Csk results in decreased GC B cell competitiveness and impaired affinity maturation, partly due to enhanced ROS-mediated #apoptosis . hubs.la/Q02xrLF70