Kögl, Ammann and colleagues Universität Freiburg show that Syntaxin-11 (#STX11) is required for successful T/B-cell interaction. Deficiency in STX11 impairs CD4 T cell–dependent B cell differentiation and humoral responses. hubs.la/Q02wGZ6P0 #Immunodeficiency #FHL
Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect, say Tamara Kögl, Peter Aichele, Sandra Ammann and colleagues Universität Freiburg: hubs.la/Q02x7mVm0 #Immunodeficiency #LymphocyteBiology #InfectiousDisease #FHL #STX11
