Short comment upon invitation of the editors of Neuro-Oncology on the fantastic recent work by @NCIKenAldape and colleagues on AI-assisted classification of H&E sections 🔬🤖 in Nature Medicine : doi.org/10.1093/neuonc… Original study: rdcu.be/dNFdZ SNO

Very pleased to announce our new film about @MnpOutreach (initiated by Hopp-Kindertumorzentrum Heidelberg (KiTZ)/DKFZ/Universitätsklinikum Heidelberg) and the joint efforts of scientists & physicians to improve the treatment of children with #cancer worldwide through modern precision diagnostics! 🤝🌏🎗 youtu.be/s28rcuQDPTA

This is brilliant, thanks a ton Alex Cagan 🙌🏼 Going to use this everywhere now 🖼️🩷#ScienceGoals #GenomeScienceUK 🧬🧬

Christiane Opitz opening the VomLaborInDiePraxis Heidelberg Retreat. Moderating the session together, in which also Areeba Patel will present our newest approaches to faster and more precise #neuropath DKFZ

Representing a lot of hard work from Ninin UoN LongRead John Tyson Deep Seq Josh Quick and Nick Loman pleased to share biorxiv.org/cgi/content/sh… which captures all our experience with ultra long read sequencing on Oxford Nanopore - a lot has happened since @scalene first generated ultras!

Very exciting opportunity to work on harnessing computational approaches to develop T cell immunotherapies for childhood cancers. please RT! Karin Straathof💙🎗 Cancer Grand Challenges #nexTGen #childhoodcancer #Immunotherapy #cancerevolution

Introducing ROBIN. Rapid nanopOre Brain intraoperatIve classificatioN. ROBIN builds on work by many groups and shows how we could reduce turnaround time for full molecular classification of CNS tumours in NHS clinical settings from weeks to hours. medrxiv.org/content/10.110…

Artem Shmatko presenting our joint study with Moritz Gerstung group on AI-assisted prediction of methylation class from H&E sections at #eano2024 EANO Universitätsklinikum Heidelberg DKFZ

Franziska Ippen presenting our data on hemizygous CDKN2A/B deletions in #meningiomas at #eano2024 EANO @HdNeurooncology Universitätsklinikum Heidelberg DKFZ

Areeba Patel presenting our platform-agnostic methylation classifier at #eano2024. This enables methylation classification in highest granularity with any type of input, array, methyl seq, nanopore etc. EANO Universitätsklinikum Heidelberg DKFZ

Sahm Lab and friends having a great time in Glasgow! #EANO2024 EANO Moritz Gerstung RaleighLab

ecDNA are rogue genetic material that amplify genes, contribute to treatment resistance and drive genomic heterogeneity. We report on the Origins and impact of extrachromosomal DNA today in nature nature.com/articles/s4158…

Check out our new paper on ecDNA! Tweetorial below. It’s been great working on this project with Chris Bailey, Oriol Pich et al. 🧬🍩

Happy to share our accepted manuscript, led by Franziska Ippen, on hemizygous CDKN2A/B deletions in IDH-mutant gliomas. Based on our manual assessment, we found no significant impact on survival in our cohort. academic.oup.com/neuro-oncology…

📢Highlights from SNO 2024 The SNO 2024 conference in Houston highlighted groundbreaking advancements in brain cancer research, with discussions on molecular diagnostics, novel treatments, and new collaborations in neuro-oncology. Ashley Love Sumrall, MD, FACP, FASCO SNO Keri Martinowich

Huge congratulations, Dr Thol!! Very well deserved 🎓🎊🧬🧬

Finally #PhDone 🎓🎊 Big thanks to my supervisors Sahm Lab Moritz Gerstung + the best lab mates 🥹❤️ #PhDatDKFZ DKFZ Universitätsklinikum Heidelberg

Could not have done it without this amazing group and especially zaira seferbekova ♦️ ❤️❤️

🔥New #review out! We explore how experimental models and high-throughput sequencing (or, all the ✨#omics✨) complement each other in #metastasis research. Bridging these approaches can unlock deeper insights into #cancer progression and #treatment

🚨new pre-print alert we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) – shedding light on a long-standing diagnostic challenge. 🧵 1/