So excited to share our collaborative work on predicting PDL1 expression from HE slides using AI, a project with Grünewald Lab, Moritz Gerstung and Xiangzhi Bai’s group!

🎉New paper🎉Have you ever tried to capture both daughter cells after a burst of mutagenesis? Paul did, and found mirror-image mutation phasing of #LesionSegregation

Single-mitosis dissection of acute and chronic DNA mutagenesis & repair Nature Genetics

Happy to have contributed!

🔥This 👇👇👇was a very much fun project with Darui Jin and Moritz Gerstung involving AI and morpho-molecular correlation to predict PDL1 status from histopathology slides across cancer types now published in Nature Communications
DKFZ Hopp-Kindertumorzentrum Heidelberg (KiTZ) NCT Heidelberg

nature.com/articles/s4146…

The Duncan Odom Laboratory and Moritz Gerstung lab are recruiting a joint technician to push exciting new directions related to cancer evolution, spatial genomics etc. Please encourage suitable folks to check out the job ad and apply.

jobs.dkfz.de/en/jobs/166554…

.Darui Jin Moritz Gerstung Grünewald Lab combine multiple instance learning and a teacher-student framework to predict PDL1 expression from histopathological imaging
#CancerResearch Cancer at Nature Portfolio nature.com/articles/s4146…

Last chance to register:

Cancer Evolution: From Genome to Ecology, 8–10 May 2024, Wellcome Genome Campus, UK.

An excellent lineup of speakers inc Nuria Lopez-Bigas, Raheleh Rahbari, Jose Tubio’s lab - Mobile Genomes, Trevor Graham and James DeGregori.

…erences.wellcomeconnectingscience.org/event/cancer-e…

Build your professional profile at the intersection of evolutionary biology and #CancerResearch at #CancerEvoEco24

Share novel ideas to shape thinking on the future of precision medicine in treating cancer

⏰Submit your abstract by 12 March 2024
🔗Info: bit.ly/3Rr1ynM

I'm co-organizing Cancer Evolution: From Genome to Ecology, 8–10 May 2024, Wellcome Genome Campus, UK.

Listen to great speakers, including Nuria Lopez-Bigas, Raheleh Rahbari, Trevor Graham, Jose Tubio’s lab - Mobile Genomes and James DeGregori.

Abstract deadline: 12 March 2024.

…erences.wellcomeconnectingscience.org/event/cancer-e…

Thesis defended and my colleagues awarded me with the fancy hat 🎓

Thank you everyone who've been with me on this journey - you are fantastic scientists and friends! And thank you Moritz Gerstung and Lucy Yates for guiding me through this chapter of my life. It was fun!

Spatial biology of cancer evolution go.nature.com/3W2m25J #Review by ✨ zaira seferbekova, Artem Lomakin, Lucy Yates & Moritz Gerstung DKFZ Wellcome Sanger Institute
Free to read here: rdcu.be/c1jwe

Extremely pleased to be receiving this award at my first EANO meeting! 🏆
Looking forward to presenting exciting updates to our Oxford Nanopore based molecular diagnostic workflow- Rapid CNS2 at #EANO2023 🧠🧬🧬
Catch my talk on Saturday at 4pm!

Universitätsklinikum Heidelberg Hopp-Kindertumorzentrum Heidelberg (KiTZ) DKFZ Sahm Lab

📢Clonal hematopoiesis driven by mCAs📢What fitness effects do mCAs confer to our blood cells?🩸 How often do they occur? Does an mCA’s fitness correlate with blood cancer risk?🔎Read mine & Jamie Blundell's latest paper Nature Genetics to find out (& more!):👉🔗rdcu.be/dlRRr

Just saw that the last paper from my PhD* generated some science-y buzz with great commentary (as usual) from Moritz Gerstung

Elevator pitch: we showed that computational methods can help detect disease-specific blood cell types

*nature.com/articles/s4146…

eurekalert.org/news-releases/…

I wanted to provide assessment of spike amino-acid mutations in new highly mutated 2nd generation BA.2 SARS-CoV-2 variant

This is analysis for those (like me) scientifically interested in SARS2 evolution

(Anyone else is completely within reason to ignore this variant right now)

Fantastic 📰 - my last 1st author 🗞️ from my PhD is out at Nature Communications! The preprint is now >1yo so I'll be going over the main findings in a wee 🧵

Stick around to know how we analysed >400 blood smears to infer disease-associsted cell morphologies 🦠

The 1st #spverse hackathon was an incredible start for us. We couldn't be prouder! 🎉 Hosting brilliant minds from Cambridge, Munich, Busan(South Korea), and more at #dkfz_heidelberg made it truly unforgettable. Here's a glimpse of the remarkable journey we had! 🌟 #spatial_omics

My lab's new histopathology themed QR code. Generated by Artem Shmatko and Artem Lomakin.
🔥🔥🔥

✨DON’T MISS THIS Nature Cancer REVIEW ARTICLE – “Artificial intelligence in histopathology: enhancing cancer research and clinical oncology” by #ArtemShmatko # Moritz Gerstung Jakob Nikolas Kather.

Find it here👇
nature.com/articles/s4301…
rdcu.be/c77VP