The DAQ-Score Database has been updated! It now includes evaluation of over 140,000 protein chain structures drived #Cryo-EM maps. Visit daqdb.kiharalab.org to access the database. The original DAQ paper is at nature.com/articles/s4159….

Just out online! "DAQ-Score Database: assessment of map–model compatibility for protein structure models from cryo-EM maps", Tsukasa Nakamura, Xiao Wang, Genki Terashi, & Kihara, Nature Methods Nature Methods nature.com/articles/s4159… Visit the db at daqdb.kiharalab.org

CryoREAD finally online, feel free to try our server online em.kiharalab.org/algorithm/Cryo…

New paper from our lab! "CryoREAD: de novo structure modeling for nucleic acids in cryo-EM maps using deep learning" by @xiaowangzyy Genki Terashi Kihara, in Nature Methods nature.com/articles/s4159… Web server, G Colab, code: kiharalab.org/emsuites/cryor… @purduecs Purdue Science

Had a workshop on CryoREAD, DNA/RNA modeling tool for Cryo-EM. Discussion led by XiaoWang. It was a very well-attended event! Send us any follow-up questions. Web server: em.kiharalab.org/algorithm/Cryo… Paper: nature.com/articles/s4159… Photos: Pranav Punuru Purdue Science Purdue Computer Science

A brief introduction about our new paper CryoREAD (automated DNA/RNA structure modeling tool from cryo-EM): protocolsmethods.springernature.com/posts/cryoread…. It has been published in Nature Methods: nature.com/articles/s4159…. The free server is available at: em.kiharalab.org/algorithm/Cryo….

Behind the Paper: Blog by the first author Xiao Wang on our recent paper "CryoREAD: de novo structure modeling for nucleic acids in cryo-EM maps using deep learning" in Nature Methods. protocolsmethods.springernature.com/posts/cryoread… Server at: em.kiharalab.org/algorithm/Cryo… More at: kiharalab.org/emsuites/

Chinese version blog of "CryoREAD: de novo structure modeling for nucleic acids in cryo-EM maps using deep learning" in Nature Methods. mp.weixin.qq.com/s/NQzs8D4ieMI_…. Server at: em.kiharalab.org/algorithm/Cryo…. More at: kiharalab.org/emsuites/

My algorithm talk about CryoREAD for DNA/RNA modeling was made available on Youtube: youtube.com/watch?v=p7Bpou…. A more detailed version of our instructions in kiharalab.org/emsuites/cryor…. The paper is here: nature.com/articles/s4159…. Our online server is here: em.kiharalab.org/algorithm/Cryo….

We will host a webinar on "Protein & DNA/RNA Structure Modeling for Cryo-EM maps", on Nov 16, 2023 (Thr) 4PM (London) 11AM (New York) 8AM (California) Will send a webinar link once you register: docs.google.com/forms/d/e/1FAI…

I am a Ph.D now😃

Welcome to use our DeepMainMast server to try automated protein structure modeling from cryo-EM maps!

DeepMainmast is a protein structure modeling protocol for cryo-EM that combines the strengths of a deep-learning-based de novo protein main-chain-tracing approach with AlphaFold2-based structure predictions for improved performance. Genki Terashi doi.org/10.1038/s41592…

New paper from our lab: "GO2Sum: generating human-readable functional summary of proteins from GO terms" by Swagarika Jaharlal Giri nabil_ibtehaz from Purdue Computer Science published in NPJ Systems Biology and Applications. (cont.) nature.com/articles/s4154…

Introducing DiffModeler, a fully automated structure fitting method for modeling large protein complex structures from cryo-EM maps of a broad range of resolutions. XiaoWang Genki Terashi Daisuke Kihara Kihara Laboratory nature.com/articles/s4159…

Please try our tools online: em.kiharalab.org

Brief intro of our new paper DiffModeler, published on Nature Methods. communities.springernature.com/posts/diffmode… For more details, please see original paper in nature.com/articles/s4159…

Proud of our team that makes the huge leap happen compared to last version but this is just the start. Better models are lined up and we keep improving every week. Join us towards Superhuman Multimodal Intelligence job-boards.greenhouse.io/xai/jobs/50826… !!