How can deep learning be used to accurately predict RNA tertiary structures when experimental determination is costly and time-consuming?Purdue University Nature Communications "NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation"

"NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation" by Yuki Kagaya et al. is now out in Nature Communications ! This deep learning method played a key role in our 3rd place finish for RNA in CASP16. nature.com/articles/s4146…

NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation Nature Communications 1. NuFold is a novel deep learning-based framework that predicts RNA tertiary structures directly from sequence data, offering a breakthrough in RNA

Professor Kihara receives 2025 College of Science Faculty Research Award purdue.edu/science/resear…

Pictures from the CS graduate symposium last week. Swagarika Giri talked about her work on Go2Sum, protein function summarizer, and Daisuke Kihara was on a faculty panel discussion. cs.purdue.edu/gsa/symposium_…

Flash talk by Yuki Kagaya on the Nufold RNA structure prediction method presented at the CASP16 evaluation meeting: youtube.com/watch?v=IJOnVV… You can run Nufold at Google Colab: colab.research.google.com/github/kiharal… Nufold paper: nature.com/articles/s4146…

New paper online : Learning with Privileged Knowledge Distillation for Improved Peptide–Protein Docking, ACS Omega. The method, Distpepfold, uses student-teacher model to improve peptide docking over AF2. pubs.acs.org/doi/10.1021/ac…

our mayor 🤗🤗🤗

New paper released! "Distance-AF improves predicted protein structure models by AlphaFold2 with user-specified distance constraints" Yuanyuan Zhang, Zicong Zhang, Y Kagaya, G Terashi, B Zhao, Y Xiong & D Kihara, Communications Biology. Communications Biology nature.com/articles/s4200…

New paper:🧬 Queryome: A multi-agent AI system for biomedical literature analysis. Queryome is a deep research system with specialized LLM agents that orchestrate to a wide range of queries based on Pubmed citations. biorxiv.org/content/10.648… Try it: queryome.app