Welcome to Yale Cancer Center Dr. Roel Verhaak, Professor of #Neurosurgery, and a leader in the field of #glioma. Smilow Cancer Hospital Yale School of Medicine Yale New Haven Hosp Yale Department of Neurosurgery

Today is Independence Day and the 6th anniversary since I came to the United States. I am thrilled to share that I will start my independent career as an Assistant Professor in the Department of Physiology at MSU starting in January 2024 🥳 yilaboratory.com

The INDIGO trial (nejm.org/doi/full/10.10…) shows that vorasidenib treatment delays tumor progression for patients with IDH-mutant glioma. Low Grade Glioma Registry and I summarized the science leading up to this groundbreaking outcome nejm.org/doi/full/10.10….

Do you want to explore more about extrachromosomal DNA #ecDNA? My lab at MSU is looking for a postdoc and a lab manager! 🔬🧬🥳 For the postdoc position, check and apply here: careers.msu.edu/en-us/job/5165… For the lab manager position, please DM me!

Interested in clinical trial innovation? Check Kevin Johnson who will present "Single cell transcriptomics, pharmacokinetics, and pharmacodynamics of combined CDK4/6 and mTOR inhibition in a phase 0 trial of recurrent high-grade glioma" Friday 4:55 PM in Room 109-110 #SNO2023

At #SNO2023, Tamrin Chowdhury will present her #GLASSConsortium work with Fred Varn and many others: "Longitudinal molecular characterization identifies treatment driven evolution of oligodendroglioma", on Friday at 8:20 AM – 8:25 AM PT in Room 118-120.

My previous colleague zhengsiyuan published an interesting PDX story. Congratulations !!! nature.com/articles/s4146…

Excited to be recruiting new postdocs that will leverage our high-content screening and live-cell imaging platform to discover new therapies for pediatric glioma patients: verhaaklab.com/archive/2023-1…. Contact me with questions and for more info!

The Verhaak lab is looking for a new lab manager. who will make sure that our wet lab is able to operate effectively and efficiently. MSc degree with 3+ years of experience required. verhaaklab.com/archive/2023-1…

Newest GLASS paper online! The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen aacrjournals.org/cancerres/arti… congrats to Houtan Noushmehr

Starting this new year by wishing Eunhee Yi all the best as she starts her own lab at MSU! We are so thankful for all you have achieved during your time with us.

We cannot express enough appreciation for the leadership that @amitdgujar12 has provided during his six years as our lab manager and senior scientist in our group! We wish you all the best as you start your new role with the U.S. FDA.

The 2022 GLASS Data Resource can now be analyzed via cBioPortal: cbioportal.org/study/summary?…. Check out the new functions to analyze longitudinal profiles!

We are proud and excited to start contributing to the pediatric glioma field enabled by the Lindonlight Collective support!

🚀This is one of those days in life that words can't quite capture! 🌟 I've been awarded an Emmy Noether Group by the DFG public | @[email protected] with over €2M in funding! 🎉 Starting my own lab in Essen with a focus on Computational Oncology. Uniklinikum Essen Uni Duisburg-Essen @unidue.bsky.social Hämatologie und Stammzelltransplantation, UK-Essen 1/4

As we celebrate the approval of vorasidenib for treatment of grade II IDH-mutant, I would like to recognize those that developed the original compounds. See pubs.acs.org/doi/10.1021/ac…, science.org/doi/10.1126/sc… and perhaps most importantly pubs.acs.org/doi/full/10.10…. Fantastic job!

FINALLLY. (Warning, this is a long thread.) It has been a long battle. My current R01 was about to end in November this year. I might have needed to close my lab by next Spring. I truly believed in my projects, but without funding, I could not continue. >>>

Roel Verhaak named the Harvey and Kate Cushing Professor of Neurosurgery news.yale.edu/2024/09/04/roe…

My brilliant student, Soyeon Kim, successfully completed her MS at SKKU (Sungkyunkwan University (SKKU)) and is now joining Wellcome Sanger Institute's PhD program(Wellcome Sanger Institute). I was very fortunate to supervise her for the past years, and I hope her future will always be happy and bright.

Our new (eDynamic/Cancer Grand Challenges funded) publication on ecDNA is now online, showing that ecDNAs play a role in treatment response and cancer progression. Thanks to all involved and especially Hoon Kim and team for the excellent collaboration.