My lab is hiring postdocs to study aneuploidy's role in cancer! We're applying next-gen chromosome engineering approaches to uncover how gene dosage imbalances impact drug sensitivity, metabolism, immune evasion, and more.

Send me your CV+cover letter if interested. Please RT!

📢 Announcing five new global #CancerGrandChallenges teams! 📢

We're thrilled to announce five new teams, each receiving up to $25m over five years to tackle some of cancer's toughest challenges.

Meet the teams: bit.ly/3Oqe58O

Cancer Research UK National Cancer Institute

Excited to share our group's first manuscript describing new anatomical connections that allow the eyes to act as an 'immunological window to the brain' 👁️🧠 (1/)

nature.com/articles/s4158…

Now open to adults seeking cognitive behavioral therapy for headache disorders and/or sleep problems! Verhaak Integrative Psychology is a telehealth private practice with availability to see patients in 38 states. For more info, visit vi-psych.com or message me!

🔬 Exciting News! Our manuscript, 'scGPT: toward building a foundation model for single-cell multi-omics using generative AI' is now finally published in Nature Methods (@NatureMethods) 🎉 !!!

(Re-)Introducing scGPT: A transformative foundation model engineered for single-cell

We are thrilled to have published our recent findings regarding the way that GBM tumours adapt to, and survive, treatment in Genome Biology. This brief thread highlights what we found: 1/8

The most important paper of 2024 🤯

.Roel Verhaak Yale Department of Neurosurgery shares new research on the impact of treatment on the #glioma #cancer genome at #GrandRounds . Watch his talk now youtube.com/watch?v=nGqXvV…. Smilow Cancer Hospital Yale School of Medicine Yale New Haven Hosp

🎉 The best way to start the week is to find out that our MedSAM is finally published today in Nature Communications!

**Segment anything in medical images**
Paper: nature.com/articles/s4146…
arXiv: arxiv.org/abs/2304.12306
Data & Code: github.com/bowang-lab/Med…

MedSAM is the first

The co-occurrence of chromosome 10 loss and 7 gain in #gliomas is the MOST frequent loss-gain co-aneuploidy pair in human #cancers , a phenomenon that has been investigated without resolution since the late 1980s. What is this mystery? We investigate! (1/n)
biorxiv.org/content/10.110…

We are excited to share our new publication! It is a multi-year, multidisciplinary basic science and clinical team effort. Thank you Dept of Neurosurgery and UCSF Brain Tumor Center for making this possible!
Radhika Mathur et al, Cell, Jan 18, 2024
cell.com/cell/fulltext/…

Thrilled to finally share my 5+ years of postdoctoral work, published today in Cell!

“Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective”

Cell Joe Costello UCSF Neurosurgery UC San Francisco

authors.elsevier.com/c/1iS4bL7PXmefE

#OnlineFirst : Passenger Gene Co-Amplifications Create Collateral Therapeutic Vulnerabilities in Cancer, by Yi Bei, Anton Henssen, Jan Dörr et al.
bit.ly/48zC4ur
VomLaborInDiePraxis Charité - Universitätsmedizin Berlin Max Delbrück Center Berlin Institute of Health

Updated/new postdoc opportunity: verhaaklab.com/archive/2023-1…

The 2022 GLASS Data Resource can now be analyzed via cBioPortal: cbioportal.org/study/summary?…. Check out the new functions to analyze longitudinal profiles!

We cannot express enough appreciation for the leadership that @amitdgujar12 has provided during his six years as our lab manager and senior scientist in our group! We wish you all the best as you start your new role with the U.S. FDA.

Starting this new year by wishing Eunhee Yi all the best as she starts her own lab at MSU! We are so thankful for all you have achieved during your time with us.

Just out: the T2-FLAIR mismatch sign is associated with favorable prognosis upon recurrence of IDH-mut astrocytoma. The result of a truly multidisciplinary, bench-to-bedside collaboration, we've learned so much from each other 🙏🏻 Karin van Garderen Roel Verhaak
academic.oup.com/noa/article-ab…

Newest GLASS paper online! The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen aacrjournals.org/cancerres/arti… congrats to Houtan Noushmehr

The Verhaak lab is looking for a new lab manager. who will make sure that our wet lab is able to operate effectively and efficiently. MSc degree with 3+ years of experience required. verhaaklab.com/archive/2023-1…