Today we had a nice example of a Pacinian Corpuscle Neuroma. It is a benign lesion composed of prominent pacinian corpuscles with variable patterns in the dermis. Typical corpuscles measure 1.0 - 1.5mm, these were slightly larger at 2mm. #dermpath #dermatology Dr. Pathology Boards

#pathologyeducation #someEd Dr. Pathology Boards R.Sono🔬💻🧬 | 語呂にゃんさん

Despite looking like a low-grade Gleason adenocarcinoma of the prostate, this is a case of adenosis. It can present with small glands, smooth luminal borders, and nucleoli. The key here is the PIN-4 stain demonstrating basal cells. Scary! #pathology Dr. Pathology Boards UNMC Pathology, Microbiology & Immunology

It's just a little collagenous colitis for a palate cleanser.

Keep Parathyroid lesion in ur differential for cellular-FNA of small thyroid nodules Sam Albadri, M.D., M.Sc. Sam Khader, MD Endocrine Pathology Momin Siddiqui Ashish.Chandra Lisa Rooper Peter Sadow, MD, PhD @samyra_rashid Diagnostic Cytopath @UEndopath Penn Path & Lab Medicine

Recently found out about the new 2019 ASCCP guidelines for cervical cancer screening, with a shift toward risk-based clinical action thresholds: journals.lww.com/jlgtd/Fulltext… ✳️Important to understand how our path diagnoses impact patient management! #CytoPath #GynPath Thanks Chris VandenBussche!

Typical FNA picture of an adenoid cystic carcinoma with uniform basaloid cells, microcystic architecture, and abundant hyaline globules. Check out the new PathologyOutlines.com article on malignant salivary gland FNA! shorturl.at/kKTZ6 #cytopath #ENTPath #FNApath #FNAfriday

Textbook case of intestinal #amebiasis: Biopsies taken from a colon with many ulcers displaying "poached egg" appearances. Histologic examination shows the presence of E. histolytica in both trophozoites and cysts form. #PathTwitter #GIpath #microbiology #pathharryspotter

Hepatoblastoma, mixed epithelial and mesenchymal type: 🔸 Most <5yo 🔸 Epithelial (resemble immature hepatocytes) and mesenchymal (spindled) components 🔸 Nuclear β-catenin+ (80% cases) in both components #FNAFriday #CytoPath #liverpath #GIpath #pedipath #Pathology PathSpotters

Thyroid nodule FNA 🔴 Malignant (Bethesda 6) 🔴 MEDULLARY thyroid carcinoma ⚫️ ➕calcitonin, synaptophysin, chromogranin ⚫️ ➖ thyroglobulin ⚫️ PAX8 (variable and weak) ⚫️ Cyto: round, plasmacytoid, polygonal or SPINDLE cells in nests, cords, or follicles #cytoPath #FNAFriday

On low power, majority of you would think "PA from the Parotid". However, most would change the opinion on high power and once I disclose that the FNA came from a femoral lesion in a young male. Immature osteoid from "Osteosarcoma" appears extremely "myxoid".

FNA clear cell renal cell carcinoma: Cells w abundant cytoplasm and w small cytoplasmic vacuoles. Can be difficult on liquid based preps where the cells r bland & may mimic histiocytes (low N:C, eccentric nuclei). The smears r helpful, w large vascular cohesive groups #cytopath

Parotid FNA with "plate-like" amylase crystals 💎 , associated with sialadenitis. VS "floret-like" tyrosine crystals, which can be seen in pleomorphic adenomas and other neoplasms. Feels like trivia fodder for Xiaoyin "Sara" Jiang, MD (She/Her)! 🤫 #FNAFriday #CytoPath #ENTPath #Pathology #pathboards

Case of the week submitted by Dr. Yemelyanova. The patient is a 18 year old female with bilateral adnexal masses.

What is your most likely diagnosis? Courtesy: Sandyya Umamahesweran Dr. Pathology Boards #pathboards

Case of the week. The enlarged splenectomy specimen of a 44-year old man shows multiple variably sized blood-filled nodules throughout the cut surface (A-D). Immunophenotype: CD163+ (subset of cells), CD34+ (subset of cells), CD8 negative in red pulp sinuses.