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Laigo Bio - Embracing Proximity We're excited to introduce our website. We aim to create cutting-edge therapies by removing and degrading any cell surface targets with precision. laigobio.com #SureTACs #TPD #laigobio #membraneprotein #protacs #proteindegradation

Wonder how much colorectal cancer organoids could be improved by reconstructing the tumor microenvironment? Check out our latest pre-print and opus magnum by Nicolas Broguiere and colleagues!

Ein 📺Beitrag von ZDF NANO über Jens Puschhof, dem letzte Woche der Deutsche Preis für #Krebsprävention|sforschung verliehen wurde. Er untersucht, wie bestimmte Bakterien #Darmkrebs fördern, um neue Präventionsansätze zu entwickeln. (ab 12:40 min) zdf.de/wissen/nano/23…

We are hiring! If you are a Research Software Engineer with experience in Python + database & modernising OmniPath using biocypher.org sounds interesting to you, please check this posting: stepstone.de/stellenangebot… - more openings at saezlab.org/#jobs

Extremely honoured to receive the ERC Consolidator this year #ERCCoG. Looking forward to the next 5 years of exciting science to unravel the intricacies how tumors become malignant. #CancerPrevention @UMCU_CMM Oncode Institute

Very happy to announce that our research on the microbiome in T -cell immunotherapies will receive this incredible boost . Thanks to the lab TMS lab, my mentors Eran Elinav, Marcel van den Brink, Roland Schmid, Nisar Malek, and institutions @M3 DKFZ NCT Heidelberg Gastroenterology@TUM Controlling Microbes to Fight Infections

🧬Explore disease at a multicellular level, capturing variations in patient samples across cell types, tissue features, studies, and technologies with Multicellular Factor Analysis, peer-reviewed by Review Commons and now published eLife - the journal elifesciences.org/articles/93161

With abundant cross-condition scell data it is timely to transition from taxonomies to multicellular descriptions of tissue function Our revised work for the unsupervised analysis of samples of scell atlases, inference of multicellular programs, and study integration is out now

Phenomenal, I love it!

Curious about inferring cell-cell communication in space or in your multi-modal dataset? Check out LIANA+, the latest framework from the Saez-Rodriguez Group. Congrats to @DanielBDimitrov and all the co-authors!

Still time until 15th September to submit an abstract to join us in Berlin in the European Society for Spatial Biology conference 👇

New publication alert🚨🚨🚨Mechanisms that clear mutations drive field cancerization in mammary tissue is out nature nature.com/articles/s4158… Congratulations all for this great team work! 🎉

Fantastic news for the #microbiome-related #cancer field! Exciting research is continuing at Epithelium Microenvironment Interaction Lab @ DKFZ, now supported by #ERCStG. Many congrats to Jens Puschhof and the entire team! Can’t wait to this awesome team revolutionizing how we think about #bacteria in #cancer...

Looking for a #senior #scientist position in an international #cancer and #microbiome research lab at DKFZ? Check out this job opening... ⬇️

Looking for a job as a #Research #Technician in #Cancer #Microbiome? We offer a collaborative team Epithelium Microenvironment Interaction Lab @ DKFZ , diversity of methods, opportunity for further training and a fun work place at DKFZ! Apply now (or share with your network): jobs.dkfz.de/en/jobs/167181…

Hyped to be at the #ESSB European Society for Spatial Biology #spatial #biology conference together with some of my colleagues from the Saez-Rodriguez Group . Great science, beautiful venue, looking forward to the next 1.5 days...

Looking forward to connect with the local single cell enthusiasts in Heidelberg tomorrow! Thanks a lot for the invitation Saez-Rodriguez Group Julio Saez-Rodriguez Natalia Gabrielli and maria!

Our Single Cell Genomics Day - highlighting our favorite new sc/spatial methods - starts today at 10AM ET! Talks are free and live-streamed (no registration required) on Youtube and satijalab.org/scgd

🧠 Excited to share my main PhD project! We mapped the regulatory rules governing Glioblastoma plasticity using single-cell multi-omics and deep learning. This work is part of a two-paper series with Omer Ali Bayraktar , Oliver Stegle and Moritz Mall groups. Preprint at end🧵👇

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵