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The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2 | #myotwitter pubmed.ncbi.nlm.nih.gov/37948583/

🚨📰 ➡️ #Macrophages control #inflammation and its resolution (#immunosuppression) by reducing #mitochondria translation ➡️ #Metformin depends on #ZEB1 for its anti-inflammation & anti-#ROS effects Nature Communications ➡️ t.ly/FUoBY by 👩🏼‍🔬 M Cortes IDIBAPS

THRILLED to share “An Interpretable Inflammation Landscape of Circulating Immune Cells” from Holger Heyn lab CNAG . ~2M PBMC🩸, 356👤, 18 Diseases ML for Biomarker Discovery & Patient Classification doi.org/10.1101/2023.1… Inflammation Atlas for Human Cell Atlas #tweetorial (1/n)

🚨 🔥📰 in Nature Communications by 👩🏻‍🔬MC Martinez Campanario Full text ➡️t.ly/KFayz 🔴#ZEB1 in #macrophages reduces #atherosclerosis development & systemic #metabolism dysregulation 🔴ZEB1 delivery via macrophage-targeted #nanoparticles reduces atherosclerosis #plaque

📌 🤔 Interested in how #CellPlasticity & #ZEB1 regulate #macrophages #metabolism ❓ ➡️Check our 2 x Nature Communications this month 1⃣ #inflammation & #mitochondria translation 🔗t.ly/8guvp 2⃣ traffic #lipids / systemic inflamm & #atherosclerosis 🔗t.ly/KFayz

🚨🔥🔥🔥 Another feat from IdoAmitLab ! Forget about pseudo-time analysis. Zman-seq allows tracing single-cell trajectories over time in vivo! 😯🙀🫢 🔗t.ly/y2l-E in Cell

Decoding the cytokine cacophony in sepsis as pairwise cytokine messages capturing the gene, cell and tissue responses of the host, with pairwise effects of TNF + IL-18, IFN-gamma or IL-1β mirroring the impact of sepsis across tissues nature.com/articles/s4159…

🚨🚨🚨 Simply ... wow!!! 👉🏽👉🏽👉🏽 From Lowe Lab in Nature Aging 🔥🔥🔥"A single administration of senolytic CAR T cells is sufficient to achieve long-term therapeutic and preventive effects"🤯😲🤯

Kaveh Bazargan Stop the bean counting: get rid of publication requirement for a PhD (many universities), get rid of paper requirement for promotion (common in China), stop touting h index and using n of citations/publications as a success metric (everywhere). 1/n

@erlichya Kaveh Bazargan I'm not saying no papers, just not make them conditions for certain things and lazily just count n's. I think we agree based on your second point.

🚨 3 x 📰 on #ZEB2 in age-associated B (#ABC) & T cells & #autoimmunity 🟠#ZEB2 drives ABC cells In Science Magazine 👉🏽 rb.gy/vp4nw7 In Science Immunology 👉🏽t.ly/GBm8l 🔴#ZEB2 drives age-associated CD4 T cells In Science Immunology 👉🏽t.ly/Mbm7V

On the Intl. Day of #WomenInScience, Regulation of Cell Plasticity Group celebrates and thanks the outstanding 5 women scientists in our team for their contributions to our research projects. 🙏🏽👩🏽‍🔬 Without them, our recent achievements would have been impossible! 👩🏽‍🔬🧪🥼🔬🦠 👩🏽‍🔬

Nature research paper: Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids go.nature.com/3Ub8CGh

🚨 Eribulin induces ZEB1-SWI/SNF-directed chromatin remodeling & mesenchymal-to-epithelial transition to sensitize cancer cells to other chemotherapeutics By Diwakar Pattabiraman& T Miller Geisel School of Medicine at Dartmouth In Cell Reports Medicine 👉🏼 t.ly/ZsmR0

Nature research paper: Transient loss of Polycomb components induces an epigenetic cancer fate go.nature.com/3w9lcga

Paper alert🚨Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver published in Science Magazine. Congrats to Sinika Henschke from the Brüning Lab and coauthors. science.org/doi/10.1126/sc…

❓ Puestos a buscar “inversiones estratégicas” para 2300 millones de euros por el Estado, ¿no hay opciones de mayor rentabilidad? Por ej., llámame populista, ... dedicar una fracción a salud, educación... o incluso, llámame loco,... a investigación? 🤔 bit.ly/3QUPNoZ

A moderate increase in RagC GTPase signaling drives parenchymal damage, attracting myeloid cells that worsen damage in a 2-step pro-aging vicious cycle. nature.com/articles/s4358…

Have you ever wondered why there are so many subtypes of immune cells? In our work published today at nature, we offer one possible reason – the capacity to evolve. 1/n nature.com/articles/s4158…

We are excited to share our new study Cancer Cell identifying Zeb2 as a master genetic switch controlling the tumor-associated macrophage (TAM) program. Led by Fadi Sheban, T. San Phan, Ken Xie & Florian Ingelfinger. (1/20) cell.com/cancer-cell/fu…