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#NEW: Nature Medicine publishes the groundbreaking Mayo Clinic CV study that adapted a 12-lead AI-ECG algorithm to test the feasibility of using a one-lead #AppleWatch ECG to detect low ejection fraction. Read more about the study here: nature.com/articles/s4159…

Development of an AI-Driven QT Correction Algorithm for Patients in Atrial Fibrillation sciencedirect.com/science/articl… #EPeeps in this work we publish today in JACC Journals we attempt to solve a tough clinical problem: Determining the QTc in #AFib Short 🧵

Sharing varcard.io engine for #AI generated variant classification🎉 We fuse open datasets to provide a clinical-friendly, searchable engine based on the Google DeepMind #AlfaFold protein structure predictions. Please use, enjoy and share! NYU Langone Health #Genetics

Congratulations to our newest Cardiology fellows joining the Brigham Fellows in the coming year!! We are so excited to welcome you to Brigham Heart!!! 🥳🥳🫀🫀

#AI for rare arrhythmia disorders. Inspired by the work of Yann LeCun on Self-Supervised Learning, we adapted VICReg, an Energy Based Model to learn deep #EKG representations. Pre-training with SSL is a promising strategy for rare disease detection. NYU Langone Health New York University 👇

A great weekend welcoming the new fellows to Brigham Heart! We cannot wait for you all to join us beginning in July! Welcome to Brigham Fellows 🫀🫀

🚨Stunning!🚨 REVERSAL in the decline of heart failure ☠️ in the US 1999-2021 1999-2005 ⬇️ ☠️ 2005-2012 ⬇️ ☠️ 2012-2019 ⬆️ ☠️ 2019-2021 ⬆️⬆️☠️ Age-adjusted HF related ☠️ rates higher in 2021 vs 1999! WT😱🆘 jamanetwork.com/journals/jamac… JAMA Cardiology Marat Fudim, MD MHS

Be skeptical of the findings in single-centre RCTs of critically ill patients published in high-impact journals claiming a mortality benefit. Only 1 out of 16 RCTs were replicated in a multi-centred RCT. ccforum.biomedcentral.com/articles/10.11… Justin Morgenstern #hello I'm Dr Kirsty 🏳️‍🌈 John Mandrola, MD Adam Cifu

Delighted to share ✨Med-Gemini✨ - our new family of multimodal models for medicine unlocking new possibilities for health - arxiv.org/pdf/2404.18416 More accurate multimodal conversations about medical images🩻, surgical videos📽️, genomics🧬, ultra-long health records📚, ECGs🫀

AI-ECG RCT Alert: pts with ↑ mortality risk 1o endpoint: ↓ all cause mortality Consent: physicians only Generalizability limitations, but supporting the value of AI models based on standardized & reproducible inputs (ECG>EMR tabular data) nature.com/articles/s4159…

Excited to share our #echofirst foundation model is now published in Nature Medicine! Trained on 1M Cedars-Sinai A4C echo-report pairs, EchoCLIP has strong performance on wide range of cardiac diagnostic benchmarks, including LVEF in Stanford Medicine videos (MAE 7.1%).

AI in 🫀 🎉🎉 Our 2nd AI-ECG model dealing with the QT interval, this time for diLQTS ✅ safe prescribing in the outpatient setting. Reproducible + Standardized nature of ECGs can make them a better input for medical AI models than poorly curated EMR tabular data 📊.

Prospective RCT of AI-Enhanced ECG for STEMI Activation NEJM AI ai.nejm.org/doi/full/10.10… Excellent trial building upon and complementing recent work in Nature Medicine nature.com/articles/s4159… Excellent editorial by Robert Avram and William Fearon ai.nejm.org/doi/full/10.10…

Professor Charged for Operating Multimillion-Dollar Grant Fraud Scheme Wang allegedly engaged in a scheme to fabricate and falsify scientific data in grant applications made to the NIH on behalf of himself and the biopharmaceutical company. $SAVA justice.gov/opa/pr/profess…

1/n We are excited to announce EchoPrime – the first echocardiography AI model capable of evaluating a full transthoracic echocardiogram study, identify the most relevant videos, and produce a comprehensive interpretation! Great work lead by Milos Vukadinovic, EchoPrime is the largest

A multimodal foundation model for medical images from 15 million image-text pairings ai.nejm.org/doi/full/10.10… NEJM AI open-source, open-access paper Hoifung Poon Microsoft Research

A randomized trial of tailored A.I.-guided ablation of atrial fibrillation vs standard-of-care, anatomical ablation demonstrated superiority of AI guidance nature.com/articles/s4159… Nature Medicine

AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns Today, Arc Institute in collaboration with NVIDIA releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life 🧵

New paper out today! TLDR: We use special self supervised learning architecture called VICReg, invented by Yann LeCun to solve the problem of insufficient labeled data We show that real prevalence of "rare" diseases may be much higher than perceived 😱 nature.com/articles/s4159…

Excited to share our new study! JAMA Psychiatry Sean P. Heffron MD, MS, MSc NYU CVD Prevention Yale Internal Medicine Yale IM Traditional Residency Program Meta-Analysis looking at Suicide and Self-harm events in patient with Obesity or Diabetes taking GLP1-RA Link: jamanetwork.com/journals/jamap…