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Pleasure working with Romagnani Lab on this Nature News & Views article, highlighting 3 exciting recent nature papers which shed new light on how gut Tregs are induced by RORgt+ APCs. How regulatory T cells are primed to aid tolerance of gut bacteria nature.com/articles/d4158…

For anyone doing #flowcytometry, would you like to have a new protocol that reduces your #antibody costs by ~10-fold and also gives you higher quality data, with better signal-to-noise ratio? Yes? Then read work by @olivertburton and Carly Whyte. 1/6 …rentprotocols.onlinelibrary.wiley.com/doi/epdf/10.10…

We are delighted to share our new review article from Nils Müller "To kill or not to kill - the role of the tumor microenvironment in shaping group 1 ILC functions" now in Seminars in Immunopathology where we discuss the flavors of group 1 ILCs in different tumors doi.org/10.1016/j.smim…

Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! nature nature.com/articles/s4158…

Interested in Tissue Homeostasis and Immunity? NK cells and ILCs? join this fantastic nk-symposium.org with lots of exciting science from Joseph Sun Lab, Eric Vivier, Maini Lab UCL, Mackay Lab, Björkström lab, Ari Molofsky, @Hepworth_Lab...

B cell depleting therapies effectively treat #MultipleSclerosis, yet our understanding of why remains limited. How does loss of B cells impact the immune system in MS? See our multicohort study employing high-dimensional single-cell immunophenotyping: cell.com/cell-reports-m…

Happy to see this out Immunity: cNK cells establish tissue residency upon acute skin infection. Tcf7+CD69+ trNK resemble CD56bright NK cells in human tissues, and mediate rapid secondary responses. Thanks to the fantastic WüSI - Systems Immunology Würzburg team + all collabs! cell.com/immunity/fullt…

Please check out our paper published in Nature Medicine on our Phase I / II trial with cord blood CAR19/IL15 NK cells. We report promising 1 year PF and OS rates of 32% and 68% in patients with relapsed / refractory B cell malignancies (with a median of 4 prior lines of

Thrilled to share our latest collaboration with @Becherlab: "IL-23 stabilizes effector Treg program in tumors" by Tobias Wertheimer and Pascale Zwicky et al. out now in Nature Immunology. Check out the great tweetorial of the @Becherlab !

If you’re excited about working at the intersection between wet and dry lab to better understand relapse after allo-HCT, consider joining our group for a PhD 😊 uniklinik-freiburg.de/karriere/stell…

Check out our latest research revealing the role of hepatic iNKT cells in promoting colorectal cancer liver metastasis!

.Colin Sparano, Darío Solís-Sayago et al. TuguesLab University of Zurich reveal that tissue-resident NK cells produce their own TGF-β1 to sustain residency in glandular tissues, providing local antiviral protection. hubs.la/Q0302Wml0 #inflammation #LymphocyteBiology #InfectiousDisease

Myers, Reilly, & Brossay Brown University discuss work by Colin Sparano, Darío Solís-Sayago et al. TuguesLab (hubs.la/Q03155TM0) which shows that tissue-resident NK cells produce TGF-β1 themselves to establish and maintain residency in glandular tissues. hubs.la/Q03157gF0

Are you an immunologist interested in spatially-resolved single cell technologies and generative modeling but dont know where to start? Check out our European Journal of Immunology review with Avital, Hosna, Robert Zeiser, IdoAmitLab, Yosef Lab & Tobias Wertheimer onlinelibrary.wiley.com/doi/10.1002/ej…

Check out our new review article on spatially resolved single cell technologies and generative modeling and their application in immunology research. Fun collaboration with Avital, Hosna, Yosef Lab, IdoAmitLab and Florian Ingelfinger onlinelibrary.wiley.com/doi/10.1002/ej…

Our March cover hubs.la/Q038CHPl0 shows an immunofluorescence staining of salivary gland from MCMV-infected mice 16 days after infection. TuguesLab (hubs.la/Q038CP8T0) show that autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells