HIF-1α-mediated mitochondrial-glycolytic reprogramming controls the transition of precursor to terminally exhausted T cells biorxiv.org/cgi/content/sh… #biorxiv_immuno

Passionate about sc and spatial biology? Love host-pathogen interactions and genome evolution? The Talavera-López lab has a PhD position to study changes in pathogen’s genomes and how the host cells adapt to these changes. Interested? DM! Please repost!

Join Carlos WüSI - Systems Immunology Würzburg and become part of a stimulating and collaborative environment!

Hike and Wine and Science - lots of fun and interesting discussions WüSI - Systems Immunology Würzburg‘s Miniretreat. Let‘s have a big one in spring!

Check out this new study by WüSI - Systems Immunology Würzburg's Milas Ugur in Science Immunology providing evidence or LN-resident memory-like Treg cells. Another factor shaping site-specific immune responses in LNs! Congratulations Milas Ugur for a great first senior author paper! science.org/doi/10.1126/sc…

Honored and grateful to be supported by European Research Council (ERC) #ERCSyG, VERY excited to work with this fantastic team Eric Vivier @realFlorentGinhoux Valeria Fumagalli on liver immunity and metastases! Thanks to my lab and all supporters WüSI - Systems Immunology Würzburg @Uni_Wue erc.europa.eu/news-events/ne…

Congratulations to WüSI’s Georg Gasteiger: supported by European Research Council (ERC) #ERCSyG he teams up with Eric Vivier @realFlorentGinhoux Valeria Fumagalli to harness the local immune system of the liver in the context of metastasis! @Uni_Wue Max Planck Society #SystemsImmunology erc.europa.eu/news-events/ne…

Very proud of Valeria Fumagalli for receiveing the @ERC Synergy grant. Excited to collaborate with her and with Georg Gasteiger Eric Vivier @realFlorentGinhoux on this exciting project! unisr.it/en/news/2023/1… europa.eu/!JVYxjm Università Vita-Salute San Raffaele

Thrilled to announce that our team has been awarded a SYNERGY grant from the ERC to harness Innate Immunity against liver metastasis of colorectal cancer. univ-amu.fr/en/public/actu…

Mitochondrial dysfunction causes redox stress that inhibits proteasomal degradation of HIF-1α to promote the transcriptional and metabolic programming of terminally exhausted T cells nature.com/articles/s4146…

Gorgeous work by Martin Vaeth WüSI - Systems Immunology Würzburg Universität Würzburg #UniWürzburg demonstrating that mitochondrial dysfunction can be (and indeed is) deterministic in establishing exhausted T cell fates!!

Happy Halloween! @WUE_SI’s scientists embraced the spookiness with pumpkin carving, scary cookies, a costume challenge, a PI pipetting competition ;-) karaoke and spooky dance moves. We wish you all a spine-chilling time and lots of fun celebrating Halloween. Pic: Xless Vaeth lab

🚨🆕"What if we could map viral infections in 3D?" Now we can! Discover our #clickVSV technology in our latest publication ACS Nano: ▶️pubs.acs.org/doi/10.1021/ac… A joint effort of the labs of Georg Gasteiger and Gerti Beliu at Universität Würzburg #UniWürzburg #Virology #VirusResearch #Science

Check out this new Nature Communications publication by Martin Vaeth from WüSI - Systems Immunology Würzburg. 👇 Congratulations to all authors! 👏

Fluorescent viruses (magenta) infecting cells (white) - live! 👇 #LatticeLightSheet #Fluorescence #SARSCoV2 #Covid #research #biotech #infection

Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection dlvr.it/T1ByqF

One day left to register and submit an abstract for a talk!

New review out now! ❤️🎉Together with Jack Palmer Nadia Rosenthal The Jackson Laboratory and Teichlab we dive into single-cell and spatial approaches across mouse and human systems in the context of cardiac niches. 🧬Universitätsklinikum Würzburg WüSI - Systems Immunology Würzburg #CardiacHealth #genomics doi.org/10.1161/CIRCRE…

Great opportunity, exiting project, PI and environment: come and join Jakob Zimmermann to study T cells and the microbiome WüSI - Systems Immunology Würzburg

Ha! AI models require data on genuine human interactions , or they collapse! disq.us/t/4pugllq