📌Treatment Effects of #SacubitrilValsartan Compared w/ Valsartan in 👥 w/ Recent Hospitalization🏥
🔸Those 👥 w/ #HFpEF with recent HF🏥 , irrespective of specific LVEF, may derive benefit from SV
🔸Ongoing #PARAGLIDEHF will assess it in this scenario
#CardioEd #CardioTwitter
Now out in Journal of Cardiac Failure, we describe the treatment effects of sac/val vs. val in patients with recent HF hosp in #PARAGONHF . Treatment benefits appear similar in those with lower (≤57%) vs. higher (>57%) EF. Potential implications for the ongoing #PARAGLIDEHF trial.
#PARAGLIDEHF : #Sac /Val Vs #valsartan on changes in #NTproBNP , safety, and tolerability in patients with EF>40% stabilized after a WHF Event
Robert Mentz, MD
A total of 466 patients with EF above 40% were enrolled within 30 days of a worsening heart failure event (69% were enrolled…
Results of #PARAGLIDEHF Robert Mentz, MD
Sacubitril/Valsartan vs Valsartan in pts after WHF event (EF > 40%)🫀
Greater ⬇️NTproBNP
⬇️rate of worsening renal function
Sac/Val a/w more favorable composite clinical outcome✅
#HeartFailure2023 #HFA_ESC #CardioTwitter
Late breaking trials II: PARAGLIDEHF - sac/ val beats valsartan in HFmrEF and HFPEF after WHF event #HeartFailure2023 #HFA2023 #CardioTwitter #ESC
#PARAGLIDEHF Trial #tweetorial by no other than our Journal Club Tema member Doug Corsi!
Highly recommended to check it out!
#ACCMedStudent
Exciting news! 1st time ever (!) Zuckerberg SF General Hospital & Trauma Center is a site for a Cardiology pharm clinical trial. #PARAGLIDEHF Consented 1st pt yesterday! Big step to⬆️access, equity & trial representation for our safety net pts. SFGHFoundation Priscilla Hsue UCSF Cardiology Robert Mentz, MD UCSF IM Chiefs
Tras #HeartFailure2023 y la presentación de #ParaglideHF ➕ #Paragon
Te planteas sacubitril/valsartan en 👥con ICFEp
SEMERGEN | #YoPrefieroMFyC Gt.HTA y ECVSEMERGEN Alfonso Valle Vicente Arrarte Lorenzo Fácila Miguel Angel Prieto Sergio Cinza Daniel Rey Aldana Francesc Formiga🐜 Gonzalo Perez @MiguelCamafort Patrícia Palau
Brigham and Women's Hospital investigators collaborate to pool data from #PARAGLIDEHF & #PARAGONHF trials and demonstrate that #ARNI sacubitril/valsartan reduces cardiovascular and renal events in #heartfailure . Muthu Vaduganathan
Publication: academic.oup.com/eurheartj/adva…
Completed #SIV for #PARAGLIDEHF last week Robert Mentz, MD. Stoked to bring more #hfclinicaltrials to #baylorallsaints #FortWorth #TCU #sacubitril /valsartan #NT -proBNP #ADHF #HFpEF