Two legit two legit to quit! ✌️ Happy 2 Year Work-A-Versary to Marketing Director @dalainakay 🎉

(Ps…It’s not weird at all when you have to create you’re own shout out 😂)Cheers!

#coregroupus #2years #happyworkaversary #happyworkanniversary #cheers

1/ 🚨 #Tweetorial alert
For women with preexisting chronic kidney disease (CKD), pregnancy is a tricky tune.
Kidney hemodynamics shimmy, hormones waltz... The changes can throw off rhythm of CKD
We parrot this like a universal truth, but is it?
Let's find out! 👇 Curious, yet?

Thrilled to share our latest paper - out today in PNASNews - led Féaron Cassidy, PhD & with our great collaborators pnas.org/doi/10.1073/pn…
We report that #MAITcells utilise glycogen to support their rapid responses including cytotoxicity Maynooth University Irish Immunology NCRC

Looking for a compliant dual lumen balloon that can navigate to challenging anatomy?

Learn about the Eclipse 2L Dual Lumen Balloon
Available at Balt: ow.ly/8xH350Osp4U

#RadialFirst #Interventional #neuroRAD

1/Sometimes the tiniest thing can be the biggest pain—that’s microvascular compression of the trigeminal nerve! But seeing such a tiny finding can be hard!

Here’s a #tweetorial about how to look at the trigeminal nerve on MRI

#medtwitter #neurotwitter #neurorad #meded #FOAMed

New photon counting CT study🚨, from Mergen Victor et al, published in Radiology: Cardiothoracic Imaging pubs.rsna.org/doi/10.1148/ry…

Could PCD CT eliminate the need for noncontrast scans for quantification of calcium? This would ⬇️ radiation dose and scan time!

A #RCTIinTraining #Tweetorial
Kate Hanneman

Our podocyte BioID paper is now published! We generated a BioID knock-in mouse to acquire the localized proteome of podocin in vivo. I did a tweetorial of the preprint, here's a link to the updated manuscript: frontiersin.org/articles/10.33…

1/Mike Tyson once said, “Everyone has a plan until they get punched in the face.”

In honor of all the great hooks and crosses—here is a #tweetorial about mandibular fxs!

#FOAMed #medtwitter #Meded #neurorad #HNrad #FOAMrad #Medstudenttwitter

Here’s the #tweetorial we promised on #persistencelength !
Heads up - this one’s a bit technical! #tweetorial thursdays 1/n

Friday staging mini-Tweetorial!

Staging in breast cancer is a subject dear to my heart that I feel is often confusing and misunderstood. The reason is simple. On a slide, we see things in two dimensions, and therefore we are taught in two dimensions and we come to remember and…

There are places that other trimmers can’t do, tame irregular hair in a few seconds.

Get yours: exceedgadget.com/E4582

#TumorBoardTuesday Jon Trent, MD, PhD Sebastian Bauer Junaid Arshad Gina Z. D'Amato, MD. Mike Pishvaian Johnathan Ebben MD, PhD Brian Van Tine SarcomaFndofAmerica Therese - Hematology and Oncology Palma Dileo Brian Pico, MD Alessandro Gronchi Anette Duensing Tom Wei-Wu Chen Michael Wagner Christina Roland, MD, MS Maurício Fernando Ribeiro, MD Ankit Mangla, MD SARCOMA CONNECT Dario Callegaro gistchile Nadia Hindi Nam Bui Emily Keung, MD Chiara Fabroni Winan van Houdt Celso Mello Priscila Barreto Coelho, MD Solange Sierra Aimee Crago, M.D. Piotr Rutkowski Lara Davis Nathan Seligson Andrea Franza Lady Sarcoma sylvie bonvalot Camila Martin Patrick Schöffski Chandrajit Raut Sydney Stern, PhD, MS Irenecg Fina cruz Elizabeth Davis Colectivo Gist España Dr JMartín-Broto Angela Lamarca vicki keedy 8/19 #TumorBoardTuesday #Sarcoma
👩🏻‍🏫Mini tweetorial 5👨🏻‍🏫

📰 Extra! Extra! 📰
⬆️ TTP with sunitinib (SU) vs placebo
👍🏽 FDA approves SU for IM-resistant unresectable/adv #GIST

📚george demetri Christopher Fletcher thelancet.com/journals/lance…

#TumorBoardTuesday Jon Trent, MD, PhD Sebastian Bauer Junaid Arshad Gina Z. D'Amato, MD. Mike Pishvaian Johnathan Ebben MD, PhD Brian Van Tine SarcomaFndofAmerica Therese - Hematology and Oncology Palma Dileo Brian Pico, MD Alessandro Gronchi Anette Duensing Tom Wei-Wu Chen Michael Wagner Christina Roland, MD, MS Maurício Fernando Ribeiro, MD Ankit Mangla, MD SARCOMA CONNECT Dario Callegaro gistchile Nadia Hindi Nam Bui Emily Keung, MD Chiara Fabroni Winan van Houdt Celso Mello Priscila Barreto Coelho, MD Solange Sierra Aimee Crago, M.D. Piotr Rutkowski Lara Davis Nathan Seligson Andrea Franza Lady Sarcoma sylvie bonvalot Camila Martin Patrick Schöffski Chandrajit Raut Sydney Stern, PhD, MS Irenecg Fina cruz Elizabeth Davis Colectivo Gist España Dr JMartín-Broto Angela Lamarca vicki keedy Sarcoma Cancer Fndn Valerie Grignol 5/19 #TumorBoardTuesday
👩🏻‍🏫 Mini tweetorial 2 👨🏻‍🏫

‼️Not all #GIST created equally‼️

▪️various primary oncogenes drive tumorigenesis🔛
🧬 KIT: 70-80%
🧬 PDGFRA: 5-10%
🧬 KIT/PDGFRA wild-type: 10-15%

⚡️Each driver mutation differs re: IM sensitivity!⚡️

#TumorBoardTuesday Dr Sarah Sammons Mike Pishvaian Johnathan Ebben MD, PhD Dario Trapani G Curigliano MD PhD Paolo Tarantino Arielle Medford, MD Aleix Prat #PrecisionOncology Christine Hodgdon Tammy R. Blackburn Matteo Lambertini, MD PhD José M Peñaloza Dr. Steffi Oesterreich Chiara Corti Beth Kulow Kelly Hewitt Laura Huppert, MD Amy Beumer, Ph.D. Janice Cowden Arthi Sridhar Reham Shaaban, DO Ramy Sedhom, MD Gladys Rodriguez,MD Amy Comander MD, DipABLM Antoine Dardenne Ann Partridge MD, MPH Rebecca Shatsky, MD Komal Jhaveri Margaret Gatti-Mays MD MPH FACP Nancy Lin, MD Prarthna Bhardwaj Timothy Erick, PhD Quinne Sember, MD Laura Forrest PhD Stephanie Graff, MD, FACP Susannah Koontz, PharmD, BCOP 🎗 Adriana Kahn, MD Dionisia Quiroga, DO, PhD Vandana Renata Arakelian Dana-Farber’s Breast Oncology Center Erika Hamilton, MD Tufts Medical Center Thanks Cancer! Tari King MD James Jakub Sheyda Abdullaeva Dr. Nicole Kuderer 🌎🇺🇸🇪🇺🇺🇦💛💙🌏 Daniel Stover, MD 6/17 #TumorBoardTuesday
👩🏻‍🏫Mini tweetorial 3👩🏻‍🏫

The discrepancy in outcomes from MAINTAIN, PACE, PALMIRA could be explained by
❗ Differences between pt population: DFI
❗ Changing CDK4/6 may have impact: palbo→palbo vs palbo → rubo
❗ Differences between CDK4/6i: CDK4 vs CDK6i

Our team,
led by Jaeseung Kim has just published a paper in Nature Genetics
We uncovered 3 novel transcriptomic subtypes in BCR-ABL1 leukemia with significant clinical implications. Read Jae’s Tweetorial below. #Leukemia #PrecisionMedicine Ontario Institute for Cancer Research (OICR) UHN Research

This wouldn’t be a cirrhosis tweetorial if I didn’t mention my favorite acronym for the treatment of inpatient cirrhosis- VIBES

Que es un French ?
Que es un Gauge ?

#Tweetorial #NephTweetorial

Abro hilo

1/ If only there was a way to make hippocampal anatomy memorable!

Here is a #tweetorial of the basics of hippocampal #anatomy that will hopefully stay in your #hippocampus !

#medtwitter #FOAMed #FOAMrad #medstudent #neurorad #radres #neurosurgery #epilepsy #neurotwitter

1/THREAD
Has it ever occurred to you that Graves' disease presents a conundrum?

Graves' involves an autoimmune antibody that ACTIVATES a receptor, which is relatively unique in the landscape of human disease.

Let's unpack this fascinating mechanism.
#medtwitter #tweetorial

Check out this awesome #tweetorial on photon counting cardiac CT by Radiology: Cardiothoracic Imaging TEB member Gilberto Aquino #radres ⬇️🤗

Susanna I Lee Suhny Abbara MD Daniel Vargas, MD Ritu Thamman MD Quynh Truong Bradley Allen Domenico Mastrodicasa MariaClaraLorcaMD Gaurav Gulsin

nature.com/articles/s4158…
Notta Lab University Health Network Ontario Institute for Cancer Research (OICR) Our paper on “Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia” is finally published! Congrats to the Notta lab and everyone involved. To highlight some of the main findings..

1/ Your 56-year-old patient with DM2, HTN, HLD, and a prior MI, comes to clinic reporting he stopped his statin a few weeks ago. “The muscle cramps were killing me, doc,” he tells you.

Let's take a deep dive into statin intolerance 💊🩺🫀

#tweetorial #statinintolerance

1/Does PTERYGOPALATINE FOSSA anatomy feel as confusing as its spelling? Does it seem to have as many openings as letters in its name?

Let this #tweetorial on PPF #anatomy help you out

#meded #medtwitter #FOAMed #FOAMrad #neurosurgery #neurology #neurorad #neurotwitter #radres

#TumorBoardTuesday Dr Sarah Sammons Mike Pishvaian Johnathan Ebben MD, PhD Dario Trapani G Curigliano MD PhD Paolo Tarantino Arielle Medford, MD Aleix Prat #PrecisionOncology Christine Hodgdon Tammy R. Blackburn Matteo Lambertini, MD PhD José M Peñaloza Dr. Steffi Oesterreich Chiara Corti Beth Kulow Kelly Hewitt Laura Huppert, MD Amy Beumer, Ph.D. Janice Cowden Arthi Sridhar Reham Shaaban, DO Ramy Sedhom, MD Gladys Rodriguez,MD Amy Comander MD, DipABLM Antoine Dardenne Ann Partridge MD, MPH Rebecca Shatsky, MD Komal Jhaveri Margaret Gatti-Mays MD MPH FACP Nancy Lin, MD Prarthna Bhardwaj Timothy Erick, PhD Quinne Sember, MD Laura Forrest PhD Stephanie Graff, MD, FACP Susannah Koontz, PharmD, BCOP 🎗 Adriana Kahn, MD Dionisia Quiroga, DO, PhD Vandana Renata Arakelian Dana-Farber’s Breast Oncology Center Erika Hamilton, MD Tufts Medical Center Thanks Cancer! Tari King MD James Jakub Sheyda Abdullaeva Dr. Nicole Kuderer 🌎🇺🇸🇪🇺🇺🇦💛💙🌏 5/17 #TumorBoardTuesday
👩🏻‍🏫Mini tweetorial 2👩🏻‍🏫
🌟CDK4/6 after CDK4/6 trials Daniel Stover, MD summarized #ASCO23 (see table👇)

Continuation of CDK4/6i after progression & switch to FULV with mixed results:
➕MAINTAIN: mostly ribo after palbo
➖PACE & PALMIRA: mostly palbo after palbo

1/THREAD
Ever wonder why amphotericin B can cause severe infusion reactions, including chills/rigors + hypotension?

These infusion reactions are so awful that it carries the nickname 'amphoterrible'.

Why does this happen? The answer is mind-blowing.

#medtwitter #tweetorial

0. A Monday morning tweetorial to take you through our PNASNews paper that came out last week where we report that #MAITcells utilise glycogen to support their rapid responses including cytotoxicity twitter.com/AndyHogan82/st… O'Shea & Hogan Lab NCRC Maynooth Biology