Congratulations, Yamini.

Congratulations Sounak. So proud of you!

Our work led by Megan Buckley on Saturation Genome Editing of VHL is now out in Nature Genetics: nature.com/articles/s4158… Many new experiments and analyses to quickly highlight… (1/n)

Outstanding work! Congratulations Dave!

Another outstanding work from the Nussenzweig Lab. Andre, congratulations to you and your entire team.

Davies lab @NCIResearchCtr celebrating our W's Many animals get worse at regenerating as they age, but we don’t often hear about the opposite: a GAIN of regenerative ability during development! We investigated just that in our new #preprint biorxiv.org/content/10.110… 🧵1/18

Our new paper in Nature Communications shows that Fanconi anemia proteins promote end resection to repair double-strand breaks by homologous recombination. Great work by Bert van de Kooij, Fenna van der Wal, with @marcelvanvugt , altmeyerlab and YaffeLab! nature.com/articles/s4146…

Congratulations Sarah Paramore, PhD! Beautiful cover! Very nice work!

Our work is accompanied by an excellent study from the Couch lab Mayo Clinic, using a Human Haploid Cell line. The high concordance between our findings provides strong confidence in variant classification! nature.com/articles/s4158…

Congratulations Sounak Sahu, Mélissa Galloux, members of our BRCA Variant Analysis Unit National Cancer Institute for this outstanding work. Sincere thanks to our collaborators Drs. Chari, Papaleo, Michailidou and their team members.

Congratulations Sounak Sahu, Shyam K. Sharan, and the entire team on this new release! 👏 👉 Give it a read in nature: go.nature.com/3DPXDwi

Today we report in Nature Medicine the development of a base editing strategy for prion disease, currently a fatal and rapidly progressing neurogenerative condition with no effective treatment. @PrionAlliance DevermanLab (1/13) drive.google.com/file/d/1DVpKrz…

Homologous recombination repair status in metastatic prostate cancer by next-generation sequencing and functional immunofluorescence: Cell Reports Medicine cell.com/cell-reports-m…

Thrilled to share our latest work in nature! We show how cancer cells navigate DNA replication despite DNA damage, revealing new insights into genome stability. Huge thanks to my incredible collaborators! Check it out here: nature.com/articles/s4158…

We are delighted to share our latest work, characterising the role of BRCA2 and its binding partner PALB2 at centromeres, just out in the latest issue of Cell Reports. cell.com/cell-reports/f…

.Northwestern Feinberg School of Medicine scientists designed a methodology for high-efficiency reprogramming of primary #BreastCancer cells and used it to generate #hiPSC lines from nine breast cancer patients. 👀 See for yourself: go.nature.com/3EZkari

Happy to share our new collaboration paper in Cell Reports. We show that translation synthesis in cancer cells occurs predominantly behind the replication fork, to fill ssDNA gaps, rather than to restart stalled replication forks “on the fly”. sciencedirect.com/science/articl…

nature.com/articles/s4159…

ENIGMA VCEP guidelines significantly improve BRCA1/BRCA2 variant interpretation, reducing VUS rates and streamlining clinical diagnostics bit.ly/4bHELwk #GIMO #ACMGAMP #BRCA1 #BRCA2 #VUS #ColdSpot #VariantClassification #UCSCGenomeBrowser #ClinicalGenetics

Reclassification of VUS in BRCA1 and BRCA2 using the new BRCA1/BRCA2 ENIGMA track set demonstrates the superiority of ClinGen ENIGMA Expert Panel specifications over the standard ACMG/AMP classification system - Genetics in Medicine Open gimopen.org/article/S2949-…