How we think and talk about mitochondria matters to our science and to newcomers in the field. The powerhouse analogy is expired and we need specific vocabulary to capture the beautiful complexity of mitochondrial biology. We propose a framework and some nomenclature.

Kudos to the Formentini Lab for their recent Nature Metabolism study! 👏 The team, led by Dr. Laura Formentini, identified an ETFDH-driven metabolon that supports #OXPHOS efficiency in #SkeletalMuscle by regulating coenzyme Q homeostasis. @CBMSO_CSIC_UAM go.nature.com/3vM6A5T

This is a beautiful paper!

Quite a powerful announcement: "SpaceX is looking for exceptional science and research ideas that will enable life in space and on other planets." The RFP is now open! spacex.com/humanspaceflig…

Super excited to see our work on foxj1 and olfactory sensory neurons out in PLOS Biology. Tweetorial to come soon! In the meantime enjoy this gorgeous pictures of the zebrafish olfactory system taken by Mert Ege

Take a look at our new publication in Cell & Tissue Research! Calcium imaging of adult olfactory epithelium reveals amines as an important odor class in fish🐟 Once again, a great collaboration with Sigrun Korsching and her group. 👉doi.org/10.1007/s00441…

One would think that re-entry of neurons into the cell cycle is good for the brain. But study suggests that cell cycle re-entry pushes neurons into rapid senescence contributing to brain aging and neurodegeneration. journals.plos.org/plosbiology/ar…

So happy to share our new work that is now out @sciencemagazine: We show how neurons in the mouse zona incerta (ZI) modulate infant social behaviors and learning. This work was led by the AMAZING graduate student Yuexuan Li Yuexuan Li 李玥璇. 🎉science.org/doi/epdf/10.11… #ScienceResearch

The first social behavior of a mammal infant is to form a social bond with the mother. In this work, we found that somatostatin-expressing neurons in the ZI of preweaning mice respond to social interactions with their mother. Here's a video highlighting our main findings.

Challenge accepted. Here are a few comments on the paper after starting to wade through its massive content. The paper in question is nature.com/articles/s4158… 1/🧵

📢 New pub from Saraiva Lab! We identified a novel #ADCY3 variant linked to severe #ChildhoodObesity. Functional analysis reveals how this mutation disrupts metabolism and lipid regulation, impacting early-onset obesity. Read it here: mdpi.com/1422-0067/25/2…

To all colleagues worldwide who work or have worked with Nova: Nova and its creators have never had, do not have, and will not have any association with the newly launched Novo Nordisk project to create "Nova 2.0." Please share using this link: fsp.usp.br/nupens/wp-cont…

Origami art 📹 jacksonsorigami

Check out our new roadmap for single cell analyses of adipose tissue at Nature Metabolism 🧐 Thrilled to share our work put together by amazing colleagues from Adipose Bionetwork in Human Cell Atlas 🤩 Huge thanks to my fellow co-coordinators Susanne Mandrup Evan D. Rosen and Margo Emont

It was a pleasure to have contributed to this fantastic piece!

tldr. They designed a CRISPR/Cas–therapy in ~6 months to correct 2 mutations in CPS1, a liver protein without which we cannot metabolize nitrogen and, therefore, cannot consume proteins. Dad/Mom carry truncated genes that affect 78%/52%, respectively, of the full protein length